Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
Quantitative leukocyte disorders most often reflect changes in what type of WBC? |
Neutrophils |
|
|
What is the standard testing method for quantitative leukocyte disorders? |
Standard WBC Count & Differential |
|
|
What pool of cells is a WBC count/diff quantifying? |
Fucntional/Circulating Pool |
|
|
Which of these can be determined by a WBC & absolute neutrophil count? a) Number of PMNs being produced/destroyed b) Abnormal distributions of PMN cells c) Status of PMN production (high/low) d) Number of PMNs in bone marrow reserves |
ONLY status of PMN production (high/low) |
|
|
What can cause a shift of neutrophils from bone marrow to peripheral blood? |
- Glucocorticoids - Increased G-CSF - Endotoxin Neutrophils are being used up, so immature cells are being pulled into circulation. |
|
|
What can cause a shift of neutrophils from the marginated pool to the circulating/functional pool? |
- Exercise - Epinephrine/stress Pulling cells from PB storage into circulation. |
|
|
What can cause a shift of neutrophils from the peripheral blood to tissues? |
- Inflammatory mediators (vascular injury) - Endotoxin Neutrophils attracted to a site of injury/infection. |
|
|
What shifts in pools will cause neutrophilia? |
- BM to PB - increased - Marginated to Circulating - increased - PB to tissues - decreased |
|
|
What test is used to identify morphological/qualitative WBC abnormalities? |
Observation of peripheral blood smear |
|
|
True/False: Cytoplasmic abnormalities are more common than nuclear abnormalities. |
True |
