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18 Cards in this Set
- Front
- Back
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describe the major and minor criteria for RF
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major: chorea, arthritis, carditis, erythema marginatum, subQ nodules
minor: fever, arthralgia, high ESR, high PR |
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heart and joint involvement of RF - reversible?
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heart damage is permanent
joint damage is reversible |
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what type/types of carditis are present in RF/RHD?
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pancarditis - can be pericarditis (friction rub), myocarditis (CHF), endocarditis (murmur)
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what diagnostic lesions are found in myocardial tissue after RF/RHD?
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Aschoff Bodies - made up of Aschoff cells (giant cell with owl-eye nucleus) and Anitschkow cells (cell w/ caterpillar nucleus)
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describe erythema marginatum, found in RF/RHD
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pink rash, never on face, found on trunk, it blanches
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describe the subQ nodules found in RF/RHD
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pea size, painless, over bony prominences like extensors of hand
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what antibody test would you order if you suspected RF/RHD?
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ASO, anti-streptolysin O
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in RF/RHD w/ endocardial involvement, what part of heart is most commonly affected?
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mitral valve. RHD accounts for 99% of mitral stenosis cases
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what are the main causes of death from RF/RHD?
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heart failure to valvular deformities
or secondary IE, emboli, arrythmia |
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causes of acute vs subacute IE
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acute: staph aureus
subacute: strep viridans |
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IE normally forms where on the heart?
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on valves that are defective for various reasons: RHD, myxomatous mitral valve, calcified stenosis, prosthetics
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can IE lead to granulation tissue?
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yes, in the subacute form (acute form progresses too rapidly to form granulation tissue)
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signs and symptoms of IE:
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glomerulonephritis, osler nodes (tender small lesions on palms), roth spots (retinal hemorrhage w/ pale centers), janeway lesions (painless lesions on palms - from emboli), splinter hemorrhages under nails, petechia
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marantic endocarditis (or NBTE) is associated with what? where are the endocardial lesions?
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associated with hypercoag states
lesions are along line of valve closure, similar to RHD |
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what valvular disease can have lesions on both sides of the valve?
describe the disease. associated with ____? |
Libman-Sacks disease
sterile vegitations on both sides of valve, characterized by hematoxylin bodies (thus nuclei are gone) -associated with SLE |
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carcinoid heart disease involved which valves?
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usually right valves, where an acidic micropolysaccharide matrix is present. pt will have increased levels of 5HT
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mitral valve prolapse can be heard as a:
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mid systolic click
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what causes Calcific Aortic Stenosis
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normal aging, wear and tear on valves
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