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23 Cards in this Set
- Front
- Back
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Relationship between size of sarcoma and chance of mets.
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<5 cm: 30% chance mets
>20cm: 80% chance mets |
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Nodular fasciitis
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Self-limited
Fibroblastic proliferation Reaction to trauma Rarely recur |
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Myositis ossificans
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Reactive
Post-traumatic Becomes boney mass Can be excised (curative) |
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Dupuytren's contracture
Peyronie's disease |
Palmar and penile fibromatosis, respectively
Superficial |
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Deep fibromatoses:
Presentation |
Non-malignant but can kill
Results in abdominal/flank pain, bowel obstruction, hyrdonephrosis |
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APC mutation
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Deep fibromatoses
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Benign fibrous histiocytoma:
Presentation |
Common benign lesion on skin
Cured by excision |
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Fibrosarcoma:
Presentation |
MALIGNANT; growth in deep tissue of thigh, knee
Slow growth, present for years once diagnosed Metastasize to lung 50% + recur after excision |
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Herringbone pattern
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Fibrosarcoma
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Malignant fibrous histiocytoma:
Histologic presentation |
Pleomorphic, bizarre giant cells
Very aggressive |
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Stains with S-100
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Lipoma
Liposarcoma |
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Chickenwire appearance
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Myxoid liposarcoma
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Which liposarcomas are indolent?
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Well-diff (looks like fat)
Myxoid (chicken wire) |
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Which liposarcomas are malignant?
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Round cell
Pleomorphic Recur after excision, mets to lungs |
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Stains with SMA
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Leiomyoma
Leiomyosarcoma |
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Uterine fibroid
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Leiomyoma
Benign but can cause fullness, issues with pregnancy |
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Leiomyosarcoma:
Benign/malignant Location |
Female > male
Malignant Skin, deep tissues of extremities, perineum |
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Spindle cells with cigar nuclei
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Leiomyosarcoma
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Stains with vimentin, desmin, myogenin.
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Skeletal muscle tumors
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Skeletal muscle affecting children
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Rhabdomyosarcoma
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Rhabdomyosarcoma:
Which subtype has best prognosis? Worst? |
Best prognosis: Embryonic
Worst: Alveolar |
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Features spindle cells and epithelial-like cells.
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Synovial sarcoma
MALIGNANT |
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Stains for cytokeratin.
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Synovial sarcoma
MALIGNANT |
