Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
5 Cards in this Set
- Front
- Back
|
What is HER2?
|
Human epidermal growth factor, a transmembrane tyrosine kinase that is overexpressed in 25-30% of breast cancers. Tandem duplications often result, increasing growth signal expression.
|
|
|
What type of immune cells are most engaged in tumor antigen recognition?
|
CD8 T cells and CTL cells
|
|
|
How can B cells help in the destruction of tumor cells?
|
Opsonization and phagocytosis or antibody response against adhesion proteins in tumor cells.
|
|
|
Which cytokine activates macrophages and neutrophils to exhibit cytotoxic properties against tumor cells?
|
IFN-γ
|
|
|
What interleukin enchances proliferation and differentiation of tumor specific T cells?
|
IL-2
|
