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17 Cards in this Set
- Front
- Back
Medical term for blood in stool.
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Melena
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Medical term for painful swallowing.
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Odynophagia
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Esophageal atresia:
Presentation Associated anomalies Anatomical site most frequently affected |
Esophageal atresia:
Presents right after birth with immediate regurgitation after feeding Risks aspiration and recurrent pneumonia Common assocd anomalies: Heart, GU, GI Most frequently ocurs at tracheal bifurcation |
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Hiatal Hernia:
Sliding vs Paraesophageal Complications |
Sliding >> Paraesophageal
Sliding = stomach edge slides up and down diaphragm paraesophageal = stomach pops through diaphragm, is pinched there, and stays in place Complications: GERD (incompetent LES), bleeding, ulceration, perforation |
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Reflux esophagitis:
Causes Histologic features |
multifactorial, incomp LES; hiatal hernia, obesity, EtOH, tobacco, CNS depressants, pregnancy
Histo: Elongation of papillae Basal cell hyperplasia Intraepithelial ephils, nphils |
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Eosinophilic esophagitis:
Symptoms Treatment |
Mostly atopic (allergy)
Syx: food impaction, dysphagia, GERD-like Tx: dietary restriction (cow's milk), steroid inhalation |
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Barrett's Esophagus:
Population most affected Pathogenesis Complications |
Middle-aged white men
Reflux-->inflammation and mucosal injury -->During healing, cells may dx/dy into abnl intestinal mucosa (glandular) that may be more injury resistant Complications: Ulceration Bleeding Stricture DYSPLASIA!--->adenoca |
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Barrett's esophagus:
Histologic Features |
Metaplastic columnar epithelium with GOBLET CELLS
(salmon colored tongue mucosa) |
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Infectious esophagitis:
Presentation Populations affected Causes |
Presents with odynophagia
Mostly affects immunocomp'd, elderly Causes: HSV CMV Candida bacterial causes RARE |
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CMV vs HSV esophagitis:
Nuclear inclusions |
In CMV, viral nuclear inclusions are located in ulcer
In HSV, viral nuclear inclusions are located in epithelium surrounding ulcer. |
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What is the most common cause of infectious esophagitis?
Populations affected? |
Most common cause = candida esophagitis
Assocd w/Abx used in those with COMPETENT immune systems. Due to Candida albicans. Fungal invasion = requirement for dx since candida is normal in GI tract. |
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What are the most common esophageal tumors?
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Adenoca (50%)
Squamous CC (50%) |
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Barrett's esophagus poses at 10% lifetime risk of _______.
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ADENOCARCINOMA of esophagus
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Esophageal adenocarcinoma:
Risk factors |
BARRETT'S ESOPHAGUS
Tobacco Obesity |
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Why is survival for esophageal cancer so poor?
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No serosal lining and can extend directly into adjacent structures
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Adenocarcinoma vs Squamous Cell Carcinoma:
Region of esophagus affected |
Adeno: lower esophagus (near stomach border)
SCC: mid-esophagus |
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Esophageal atresia:
Type A vs Type B vs Type C |
Type A: esophagus ends in blind loop; presents w/regurgitation
Type B: resophagus terminates at trachea, results in aspiration pneumonia Type C (most common): Esophagus terminates in blind loop (regurgitation) Second half of esophagus connected to trachea; gastric content ends up in lungs-->aspiration pneumonia |