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17 Cards in this Set

  • Front
  • Back
Medical term for blood in stool.
Melena
Medical term for painful swallowing.
Odynophagia
Esophageal atresia:
Presentation
Associated anomalies
Anatomical site most frequently affected
Esophageal atresia:
Presents right after birth with immediate regurgitation after feeding

Risks aspiration and recurrent pneumonia

Common assocd anomalies: Heart, GU, GI

Most frequently ocurs at tracheal bifurcation
Hiatal Hernia:
Sliding vs Paraesophageal
Complications
Sliding >> Paraesophageal
Sliding = stomach edge slides up and down diaphragm

paraesophageal = stomach pops through diaphragm, is pinched there, and stays in place

Complications: GERD (incompetent LES), bleeding, ulceration, perforation
Reflux esophagitis:
Causes
Histologic features
multifactorial, incomp LES; hiatal hernia, obesity, EtOH, tobacco, CNS depressants, pregnancy

Histo:
Elongation of papillae
Basal cell hyperplasia
Intraepithelial ephils, nphils
Eosinophilic esophagitis:
Symptoms
Treatment
Mostly atopic (allergy)

Syx: food impaction, dysphagia, GERD-like

Tx: dietary restriction (cow's milk), steroid inhalation
Barrett's Esophagus:
Population most affected
Pathogenesis
Complications
Middle-aged white men

Reflux-->inflammation and mucosal injury
-->During healing, cells may dx/dy into abnl intestinal mucosa (glandular) that may be more injury resistant

Complications:
Ulceration
Bleeding
Stricture
DYSPLASIA!--->adenoca
Barrett's esophagus:
Histologic Features
Metaplastic columnar epithelium with GOBLET CELLS

(salmon colored tongue mucosa)
Infectious esophagitis:
Presentation
Populations affected
Causes
Presents with odynophagia

Mostly affects immunocomp'd, elderly

Causes:
HSV
CMV
Candida

bacterial causes RARE
CMV vs HSV esophagitis:
Nuclear inclusions
In CMV, viral nuclear inclusions are located in ulcer

In HSV, viral nuclear inclusions are located in epithelium surrounding ulcer.
What is the most common cause of infectious esophagitis?

Populations affected?
Most common cause = candida esophagitis

Assocd w/Abx used in those with COMPETENT immune systems.

Due to Candida albicans.

Fungal invasion = requirement for dx since candida is normal in GI tract.
What are the most common esophageal tumors?
Adenoca (50%)
Squamous CC (50%)
Barrett's esophagus poses at 10% lifetime risk of _______.
ADENOCARCINOMA of esophagus
Esophageal adenocarcinoma:
Risk factors
BARRETT'S ESOPHAGUS
Tobacco
Obesity
Why is survival for esophageal cancer so poor?
No serosal lining and can extend directly into adjacent structures
Adenocarcinoma vs Squamous Cell Carcinoma:
Region of esophagus affected
Adeno: lower esophagus (near stomach border)

SCC: mid-esophagus
Esophageal atresia:
Type A vs Type B vs Type C
Type A: esophagus ends in blind loop; presents w/regurgitation

Type B: resophagus terminates at trachea, results in aspiration pneumonia

Type C (most common):
Esophagus terminates in blind loop (regurgitation)

Second half of esophagus connected to trachea; gastric content ends up in lungs-->aspiration pneumonia