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44 Cards in this Set

  • Front
  • Back
To Treat Schizo use what type of meds
neuroleptics and antipsychotics
Medication for schizo is _____ percent effective and provides ______ not a cure
90
balance
cure
When was thorazine first used?
1952
what was thorazine first used for?
anesthesia, then they noticed a calming effect.
what do dopamine blockers do?
Block D-2 receptors
decrease positive symptoms
increase prolactin
extrapryamidal symptoms
what do receptor blockers do?
may be too many neurotransmitters
may be too many receptors
muscarinic blockers do what?
decreases acetycholine
decrease parasympathetic responses
Alpha-1 Adrenegic Blockers do what? (2)
decrease norepinephrine effects
inhibits vasoconstriction which leads
to orthostatic hypotension
Histamine Blockers do whAT?
produce sedation (sleepy effect)
seratonin blockers do what?
decreases positive symptoms
hopefully will also decrease negative symptoms
tightness of jaw, tongue, neck shoulder,laryngeal spasms are from what extra pyramidal side effect?
Acute dystonia
drooling, tremors at rest, shuffling gait, cog wheel stiffness
pseudoparkinson symptoms
eyes rolling back are signs of what?
oculogyric crisis
akathesia is seen as?
restlessness
akinesia is seen as
MUSCLE WEAKNESS
toungue movement, lip smacking, lateral jaw movements, irreversible.
tardive dyskinesia
what type of drugs lower the seizure threshold.
antipsychotics
what is neuropleptic malignant syndrome?
result from being on antipsychotics...
what are signs of neuroleptic syndrome?
fever, increased pulse, sweating, pb instability, Lead pip rigidity
With neuroleptic malignant syndrome, what happens to WBC
Increase (15,000-30,000)
With neuroleptic malignant syndrome, what happens to creatinine phosphokinase (CPK)?
INCREASES MAY GO UP TO 2000 NORMAL BEING 30-170
traditional antipsychotics block what?
DOPAMINE
ATYPICAL ANTIPSYCHOTICS SUCH AS (CLOZARIL) DO WHAT?
block dopamine but limited eps.
may cause agranulocytosis
increased seizure risk
side effects of risperdal?
some eps
side effects with zyprexa
weight gain, almost no EPS
Info about seroquel?
excellent with virtually no side effects.
geodon side effects
cardiac irregularities
abilify
newest
antacids effect on absoprtion?
decreased
lowers the seizure threshold
clozaril
block dopamine-thorazine was prototype
positive symptoms targeted, no effect on negative.
traditional anti-psychotics.
traditional antipsychotics include
haldol, deconate, prolixin
atypical antipsychotics may cause what?
agranulocytosis.
examples of other atypical antipsychotics
risperdal
syprexa seroquel geodon abilify, clozaril
do not use this atypical antipsychotic with cocain use?
geodon
effective when resistand to other psychotics
clozaril (87)
what blocker produces sedation?
histamine
decreases postivie symptoms
increases prolactin
extrapyramidal symptoms
blocks d-2 receptors.
What type of blocker?
dopamine Blockers
decreases acetycholine and parasympathetic responses?
What blocker?
muscarinic
decreases positive symptoms hopefully will also decrease neg symptoms
what blocker?
seratonin blockers
decreases norepinephrine effects.
can cause orthrostatic hypotension.
what blockers?
alpha 1 adrenergic blockers
a psychiatric disorder in which either a major depressive or manic episode developes concurrently displaying the dymptoms of schozophrenia.
schizoaffective3 disorder
disorder that involves person having both schizophrenia and affective disorder. level of functionain is much higher than with schizophrenia.
schizoaffective disorder
some medical conditions may present with psychosis, for example. demenita
psychosis related medical condition