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21 Cards in this Set
- Front
- Back
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What are some examples of opioid analgesics?
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Morphine, fentanyl, codeine, heroine, methadone, meperidine, dextromethorphan, diphenoxylate
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Which works at the mu receptor?
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morphine
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Which works at the delta receptor?
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enkephalin
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Which works at the kappa receptor?
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dynorphin
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What are the uses for opioid analgesics?
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Pain, cough suppression, diarrhea, acute pulmonary edema, maintenance programs for addicts
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What are some toxicities of opioid analgesics?
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Addiction, respiratory depression, constipation, miosis, additive CNS depression
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What 2 receptors do Butorphanol work at?
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Mu agonist
Kappa agonist |
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What is Butorphanol used for?
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Severe pain, causes less respiratory depression than full opioid agonists
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What is tramadol used for?
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Chronic pain, not very addictive
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What is the mechanism of Phenytoin?
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Blocks Na channels
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What is phenytoin used for?
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Tonic-clonic seizures, class 1B antiarrhythmic
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What are the 4 specific phenytoin SE's?
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Gingival hyperplasia in kids
Hirsutism Megaloblastic anemia Fetal hydantoin syndrome |
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What are the 4 barbiturates?
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Phenobarbital, pentobarbital, thiopental, secobarbital
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What is the mechanism for barbiturates?
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Inc duration of Cl- channel opening
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What are barbiturates used for?
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Sedative for anxiety, seizures, insomnia, induction of anesthesia
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What are some toxicities of barbiturates?
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Respiratory and cardiovascular depression, CNS depression
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What are some examples of Benzodiazepines?
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Diazepam, Lorazepam
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What is the mechanism of Benzos?
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Facilitate GABA by inc frequency of Cl- channel opening
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What are Benzos used for?
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Anxiety, spasticity, status epilepticus, detoxification, night terrors, anesthetic
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What are the 3 Non-benzodiazepine hypnotics?
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Zolpidem, zaleplon, eszopiclone
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What are the non-benzo hypnotics used for?
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Insomnia
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