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5 Cards in this Set
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A-113. You patient is put on God for RA tx. What is its MOA, SEs, and contraindications?
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MOA: supresses macrophages and other phagocytes, depressing their lysosomal activity
ADRs: aplastic anemia, dermatitis, nephritis, agranulocytosis, chrysiasis (blue/grey color skin) Contra: hepatic/kidney dz and pregnancy |
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A-113. This drug inhibits the production and secretion of TNF. Tx for leprosy, HIV lesions, and MM.
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Thalidomide
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A-113. Allopurinal inhibits_________, thereby inhibiting uric acid production
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Xanthine Oxidase
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A-113. What drug inhibits tubular reabsorption of uric acid at high does? Part of nemonic
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Probenecid
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A-113. Lesch Nyhan Syndrome pts are prone to gout. Why?
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Lack HGPT --> build up and increases uric acid levels
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