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90 Cards in this Set

  • Front
  • Back
how prevalent is type 2
90% type 2
Old name
EDDM = juvinile or type 1
NIDDM= or type 2
New name for diabetes is
Type 1
Type 2
What kinds of diabetes are there
Type 1
Type 2
Gestational
Loss of pancreas due to trauma
LADD= latent onset diabetes
What is Diabetes Type 1 and 2
Type 1, Disorder of metabolism

Type 2, Chronic multisystem dz related to abnomal insulin production, impaired insulin utilization or both
How do we get type one
Certain genes affect immune response can play a role
How do we bget type Two
Genes affecting insulin factor
When does type 2 occure and who can get it
people over 35
and even children
Prevalence in african Am,Asian AM, Hispanics, Native adn alaskan AM,
what nationality gets type 1
White people
Secondary diabetes
Occurs due to another medical condition.
Things like pancreatitis and medications like steroids
(resolved when underlying conditions is treated)
Gestational diabetes
Developes late in pregnancy in about 4% of patients
Caused by hormones of pregnancy or shortage of insulin.
Clears up after birth
What is special about agent orange herbacide
increase in vets with type 2 diabetes
Pancreas islet Beta cells are destroyed, this causes what
Type 1 diabetes
What causes the Beta cells to be destroyed
immune response caused by a trigger response. like infections or allergy. This could be genetic
Is the genetic component stronger in type 1 or type 2
Type 2 the rate for both twins getting this is 80 to 90%
Type 1 is a rate of 50 to 60%
Who gets type 1 diagetes
more common in whites
M or F same
Finland and sweden have highest incidence
5 to 10% of Americans are type 1
average age for diagnosis is 13
Classic type one symptoms
Polyuria increased urine
Polydipsia thirst
Polyphagia Hungry
-Weight loss
-Fatigue
-Infections
8 hour fasting BGL
Random BG anytime
OGTT
>126 mg/dl
>200
>200 mg/dl in 2 hour sample
Hamaglobin A1c for nondiabetic
What is acceptable for children
4 to 6%

-7.5
OGTT is what
oral glucose tolerance test use about 75 grams they need to fast for 8 to 12 hours
PCP
FP
NP
CNS
Primary care physician
Podiatrist
fot care
Ophthalmologist
eye Dr
Management of diabetes
-Insulin must be balanced with food and daily activities
-Blood glucose monitoring
-Diabetic must take responsibility for their day-to-day care
- Must monitor for hyper and hypoglycemia
Hot and dry for
sugar high
Cold and clammy
need some candy
Hypoglycemia
Onset is rapid due to
-insufficient food
-Excess exercise
-Excess insulin
Causes
-Anxious
-Sweaty
-Hungry
-Confused, blurred or double vision,shaky,irritable
-cool clammy skin
Mild reaction and Nocturnal
Moderate reaction
Severe reaction
10 to 15g simple cho followed by a protien snack

Moderate Reacton 10 to 15g of simple CHO repeat in 10 to 15 min if symptoms pesist follow with larger snack.

Severe reaction, Glucagon if unresponsive follow with meal when able to eat
Problems for Adolescents
they have most difficult tiem adjusting
them having DM is being different
Fluctuating hormones wreak havoc
seek independence from parents
Daily compliance and structured schedule
Girls but boys too- eating disorders
Nursing Diagnosis
Risk for injury related to dibetes
Know wong
743
Diabetes is a leading cause or what
-End stage renal disease
-Adult blindness
-Lower limb amputations
-heart disease
-Stroke
-73% have hypertension
What is prediabetes
-Known as IGT impaired glucose tolerance, greater than 100 but less than 126
-IFG, impaired fasting glucose 2 hour plasma glucose higher than normal between 140and199
What is the average daily secretion of insulin
0.6 units/kg
What does insulin do after a meal
• Stimulates storage of glucose as glycogen in liver and muscle
• Enhances fat deposition
• ↑ Protein synthesis
• Skeletal muscle & adipose tissue-are directly insulin-dependent tissues.
• Other tissues such as brain, liver & blood cells do not directly depend on insulin for glucose transport
Counterregulatory hormones
 Oppose effects of insulin
 Increase blood glucose levels
 Provide a regulated release of glucose for energy
 Help maintain normal blood glucose levels
 Examples
• Glucagon, epinephrine, growth hormone, cortisol
Type 2 Diabetes
 Most prevalent type of diabetes
 Over 90% of patients with diabetes
 Usually occurs in people over 35 years of age
 80% to 90% of patients are overweight
 Prevalence increases with age
 Genetic basis
 Greater in some ethnic populations
 Pancreas continues to produce some endogenous insulin
 Insulin produced is either insufficient or poorly utilized by tissues
 Obesity (abd/visceral)
 Genetic mutations
Type 2 Diabetes
4 Metabolic Abnormalities
 Insulin resistance
 Body tissues do not respond to insulin
 Results in hyperglycemia
 Pancreas ↓ ability to produce insulin
 Inappropriate glucose production from liver
 Alterations in production of hormones
Metabolic Syndrome
 Individuals with metabolic syndrome at increased risk for type 2 diabetes

 Cluster of abnormalities that increase risk for cardiovascular disease and diabetes
 Characterized by insulin resistance
Gestational Diabetes
 Develops during pregnancy
 Detected at 24 to 28 weeks of gestation
 Usually normal glucose levels at
6 weeks postpartum
 Increased risk for C-section
 Increased risk for developing type 2 in 5-10 years
 Therapy: 1. nutritional, 2. insulin
Secondary Diabetes
 Results from
 Another medical condition
• Cushing syndrome
• Hyperthyroidism
• Pancreatitis
• Parenteral nutrition
• Cystic fibrosis
• Medications: steriods, dilantin,antipsycotics
• Usually resolve when underlying condition treated
Clinical Manifestations
Type 2 Diabetes Mellitus
 Nonspecific symptoms
 May have classic symptoms of type 1
 Fatigue
 Recurrent infections
 Recurrent vaginal yeast or monilia infections
 Prolonged wound healing
 Visual changes
FPG & OGTT Studies
 Three methods of diagnosis
 Fasting plasma glucose level >126 mg/dl
 Random or casual plasma glucose measurement ≥ 200 mg/dl plus symptoms
 Two-hour OGTT level ≥ 200 mg/dl using a glucose load of 75 g
Hemoglobin A1C
 Normal reduces risks
• Ideal: ADA <7.0, ACE <6.5
 Useful in determining glycemic levels over time
 Not diagnostic but monitors success of treatment
 Shows the amount of glucose attached to hemoglobin molecules over RBC life span
• 90 to 120 days
Goals of Diabetic Management
• Decrease symptoms
• Promote well-being
• Prevent acute complications
• Delay onset and progression of
long-term complications
Team Approach
 Patient teaching
 Self-monitoring of blood glucose
 Nutritional therapy
 Drug therapy
 Exercise
Drug Therapy
Insulin
 Insulin from an outside source
 Exogenous insulin
 Required for type 1 diabetes
 Prescribed for patient with type 2 diabetes who cannot control blood glucose by other means
 Types of insulin
 Human insulin
• Only type used today
• Prepared through genetic engineering
• Common bacteria (Escherichia coli)
• Yeast cells using recombinant DNA technology
 Types of insulin
 Insulins differ in regard to onset, peak action, and duration
• Characterized as rapid-acting, short-acting, intermediate-acting, long-acting
 Different types of insulin may be used for combination therapy
Types of insulin
 Rapid-acting: Lispro (Humalog), Injected 0 -15 min. before a meal. Onset about 15 min.
 Short-acting: Regular. Injected 30 – 45 min before meal. Onset about 30 – 60 min
 Intermediate-acting: NPH. Varies
 Long-acting: Glargine (Lantus), Injected once daily, am or pm. Released steadily with no peak action. Cannot be mixed with any other insulin solution.
 Regimen that closely mimics endogenous insulin production is
basal-bolus
 Long-acting (basal) once a day
 Rapid/short-acting (bolus) before meals
 Storage of insulin
 Do not heat/freeze
 In-use vials may be left at room temperature up to 4 weeks
• Lantus only for 28 days
 Extra insulin should be refrigerated
 Avoid exposure to direct sunlight
 Administration of insulin
 Cannot be taken orally
 Subcutaneous injection for
self-administration
 IV administration
 Fastest absorption from abdomen, followed by arm, thigh, buttock
- Abdomen
• Preferred site
 Rotate injections within one particular site
 Do not inject in site to be exercised
 NO ALCOHOL SWAB NEEDED ON SITE BEFORE INJECTION
If you change their meds on the first of Feb would it be effective to check the Ha1c March 1st
No you need 3 months, dont waste money
 Inhaled insulin
 Exubera
• Rapid-acting, dry powder inhaled through mouth into lungs
• Not recommended for patients with asthma, bronchitis, or emphysema
 Problems with insulin therapy
 Hypoglycemia
 Allergic reactions
 Lipodystrophy
 Somogyi effect
 Dawn phenomenon
Somogyi effect
• Rebound effect in which an overdose of insulin causes hypoglycemia
• Usually during hours of sleep
• Counterregulatory hormones released
• Rebound hyperglycemia and ketosis occur
Dawn phenomenon
• Characterized by hyperglycemia present on awakening in the morning
• Due to release of counterregulatory hormones in predawn hours
• Growth hormone/cortisol possible factors
Oral Agents
Not insulin
 Work to improve mechanisms by which insulin and glucose are produced and used by the body
 Work on 3 defects of type 2 diabetes
 Insulin resistance
 Decreased insulin production
 Increased hepatic glucose production

 Sulfonylureas
 Meglitinides
 Biguanides-Metformin most commonly used
 α-Glucosidase inhibitors
 Thiazolidinediones
Other Agents
Incretin mimetic-Byetta
 Synthetic peptide
 Stimulates release of insulin from  cells
 Subcutaneous injection
 Suppresses glucagon secretion
 Slows gastric emptying
 Not to be used with insulin
Glycemic index (GI)
 Term used to describe rise in blood glucose levels after consuming carbohydrate-containing food
 Should be considered when formulating a meal plan
why is the abdomen the best site to use for insulin injection
continous even absorption
 Alcohol
 High in calories
 No nutritive value
 Promotes hypertriglyceridemia
 Detrimental effects on liver
 Can cause severe hypoglycemia
Mental illness
when it interferes with your daily living.
- a disease of the brain
-
the brain
is most complex, imagine if a tiny thing goes wrong
-senses
-memory
-social cognition
-emotion
-planning
-reality
Psychiatric symptoms
arise from
misinterpritation
and
environment
Broad psych catagories
Affective disorders
anxiety disorders
psychotic disorders
personality disorders
dementias
substance abuse
Dementia
memory impairment
other cognitive impairments
substance dependence
tolerance
withdrawal
impairiment
aggression
DSM 4 TR
Diagnostic and statistic tool rests with observation of symptoms and catagorized
Function of the brain
drugs work directly at altering micro communication
over time such alterations in micro commnication affect macro communication
Finally it is hoped that it will effect the large physical symptom
Wellbutrin
stop smoking and a
antidepresant
SSRIs
prozac
paxil
zoloft
celexa
luvox
wellbutrin
remeron
serzone
Benzodiazepines
treat anxiety
Diazepam, lorazepam
big problems with abuse
Mood stabilizers
help treat bipolar
(mania and depression)
Used for impulsivity and aggression
Sometimes used in refreactory schizophrenia
Lithium
Antipsychotics
Used to treat various symptoms of psychosis
Most effective for positive symptoms
Newer drugs are probably more effetive than older drugs for negative and cognitive symptoms
Used to treat aggression and impulsivity and used to augment antidepressants
Treatment of mental illness
require long term treatment
-cessation of medication often results in recurrence of illness
-Lack of insight is often part of illness, particularly with schizophrenia.
Dangerousness
Direct, suicide, homicide, aggression
Indirect, poor self care adn failure to care for self
Mental illness summary
-common brain diseases
-Diagnosis is based on clusters of presenting symptoms
-Need to relive symptoms
-Persistent symptoms can lead to dangerousness, necessitating hospitalization
Stigma
means mark
it was put on slaves to mark status
why do mental ill people delay treatment
fear and discrimination
Explain the process of case management

· Describe the referral process
Problem solving is the key,
To coordinate and look at what we can do for our patients.
Discuss the trends in community-based care
-New models of nursing care, case method,one on one etc
Functional nursing,the art of nursing more case managment-Team nursing,more cna help-primary nursing,nurse does everything,,
-Patterns of payment are many,communication is a problem in these, they are complex,qualifications are issues.
Describe the agencies delivering care in the community
HMO-kaiser
PPO-an contracted with certain hospitals
Private pay-ins, that allows you to go where you want
prefered provide, like blue cross
Goverment, the goverment pays
fee for service, pay as you go
Identify cost containment measures
HMO,
Deligation
when does discharge planning start
with addmission, the goals and planning should start.
Three factors that influence a patients pain experience
anxiety
Age
Culture
major noninvasive pain relief measures
electrical stimulaton TENS
breathing
message
hypnosis
Neuro surgical procedure
Distraction
Hydrotherapy
Most prevelent mental illness in the US
Substance abuse, 13% of population
Cross addiction
combining uppers and downers to boost the high and potentiate the effect.