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9 Cards in this Set
- Front
- Back
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Aminoglycoside eye drops
- drugs in class & their products |
1. Framycetin (Soframycin, 0.5%, 8mL)
2. Gentamicin (Genoptic, 0.3%.5mL - also as single use drops x20 Minims Gentamicin) 3. Tobramycin (Tobrex 0.3% eye drops and eye ointment) |
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Aminoglycoside eye drops
- indications - considerations - Preg/BF - A/Es |
- infection or prevention of infection after surgery
- allergy - safe, safe Adverse effects - irritation of eye, delayed corneal healing - rare hypersensitivity reactions |
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Aminoglycoside eye drops
- spectrum of activity - when do you use them? |
Spectrum: gram negatives are really it. Gentamicin and tobramycin have antipseudomonal activity and should therefore be reserved for use only by opthamologists for serious infections not responsding to other treatments, after a culture has been taken
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Dosage of aminoglycoside eye drops
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Conjunctivitis: same as for Bleph-10 and Brolene: 1 drop q2-4h for 2/7 then qid for 5/7 - Use Tobrex ointment tds or at bedtime as adjunct
For other infections (soframycin): q2h then tds if there is an improvement For prophylaxis (Genoptic, Tobrex): qid until healed |
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Quinolone eye drops
- drugs in class and products |
1. Ofloxacin (Occuflox, 0.3%.5ml)
2. Ciprofloxacin (CiloQuin, Ciloxan, 0.3%.5ml) |
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Quinolones eye drops
- There are no CI/cautions - Pregnancy - BF - A/Es |
Cat B3 - unlikely to harm, ltd data
BF - suitable if neccessary Adverse Effects: irritation, unpleasant taste, infrequent photophobia |
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Quinolone eye drops
- spectrum - use - dosing |
- Excellent gram -ve, good gram positive. Similar to tobramycin
- Reserve use to prevent emergence of resistence - Also has been associated with corneal ulceration so use only by specialists for keratitis - same as for others in conjunctivitis |
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Chloramphenicol
- products - there are no cautions/CIs - preg/bf - A/Es |
- Chlorsig, Chloromycetin drops and ointment - 0.5%.10ml, 1%.4g oint
- Also minims single use - Cat A, Safe, Safe - NO common A/Es, may not even cause aplastic anaemia |
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Aciclovir
- products - indications - there are no CI/Cautions - Preg category A/Es - dosing |
Zovirax 3%.4.5g ointment
- Herpes Simplex (and herpes zoster sometimes) - B3 - safe to use - S/Es just stinging commonly - 1cm 5 times daily for 14 days or 3 days after epithelium is healed, whichever is shorter |
