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7 Cards in this Set
- Front
- Back
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drugs in class?
Brand names for the 2 most common ones |
cabergoline (Dostinex, Cabaser)
pergolide quinagolide bromocriptine (Kripton, Parlodel) |
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DA agonists
- indications |
1. acromegaly, third line to surgery and radiotherapy
2. hyperprolactinaemia 3. prevention of lactation 4. PD |
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DA angonists
- CI (2) |
1. postpartum haemorrhage
2. preeclampsia |
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DA agonists
- pregnancy and breastfeeding |
May be used to restore fertility but should be stopped if pregnancy confirmed, unless medically essential. Bromocriptine has the most experience (Cat A); the others are cat B.
BF: inhibits lactation |
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DA agonists
- Side effects |
1. n/v, constipation (Take with food)
2. dizziness, headache, sedation (Label 1, 16) 3. psychotic disturbance: hallucinations, confusion common, psychosis is rare 4. dyskinesia 5. Fibrotic effects (except quinagolide): around pleura of lung and heart. (Report shortness of breath, cough, or chest pain) 6/7: Withdrawal effect with Parlodel: resembles neuroleptic malignant syndrome: fever, muscle rigidity, rhabdomyolysis, sweating, tachycardia: L9 |
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Kripton/Parlodel
- dose forms - dose |
2.5mg tabs
5mg, 10mg caps 2.5mg bd 14/7 to prevent lactation 1.25mg-5mg bd-tds for hyperprolactinaemia Take at night - L1 May worsen effects of alcohol in some people (like veracaps) |
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Parlodel
- DIs |
1. DA antagonists
2. hypotensive 3. vasoconstrictors including sympathomimetics & ergot alkaloids are not recommended |
