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27 Cards in this Set
- Front
- Back
_____ is a chronic, autoimmune neuromuscular disorder characterized by fatigue and severe weakness of voluntary skeletal muscles.
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Myasthenia Gravis
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Myasthenia Gravis has an _____ course with periodic remission and exacerbation.
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unpredictable
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The effects of Myasthenia Gravis are exacerbated by ____ and ____ but relieved by ____.
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exercise
repeated movement rest |
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15% of people with Myasthenia Gravis have a _____.
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thyoma
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Myasthenia Gravis occurs when antibodies destroy or block neuromuscular junction receptor sites resulting in a...
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decrease in the number of acetylcholine receptors.
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Because the receptor sites are destroyed or blocked with MG, there is a decrease in the muscles ability to _____ even though there is sufficient acetylcholine.
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contract
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S/Sx of MG often begin at the
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face.
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Ocular and Facial manifestations of MG include:
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-ptosis
-diplopia -facial weakness -dysphagia -dysarthria |
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Musculoskeletal manifestations of MG include:
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-weakness and fatigue
-decreased function of hands, arms, legs, and neck muscles |
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2 common issues of MG that lead to respiratory problems are:
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-Cholernigic Crisis
_Myasthenic Crisis |
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Respiratory manifestations of MG are:
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-weakness of intercostal muscles
-decrease in diaphragm movement -breathlessness and dyspnea -poor gas exchange |
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Nutritional manifestations of MG are:
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-inability to chew and swallow
-decreasing ability to move tongue -impairment of fine motor movements: inability to feed self |
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Complications r/t the nutritional manifestations of MG are:
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-weight loss
-dehydration -aspiration |
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5 methods of diagnosis for MG are:
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-Tensilon test
-Electromyography -Labwork -CT scan or Chest x-ray -Nerve conduction studies |
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The _____ is a short-acting anticholinerase used specifically to diagnose Myasthenia Gravis.
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Tensilon Test
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A CT Scan or chest xray may be done when diagnosing MG to look for a _____.
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thyoma
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Drugs used to treat Myasthenia Gravis are _____ inhibitors.
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anticholinesterases/ cholinesterase
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4 antocholinesterase meds used for MG are:
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Tensilon
Mestinon (pyridostigmin) Mytelase (ambenonium) Prostigmon (neostigmin) |
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When administering anticholinersterase meds for MG it is important to do a baseline assessment of ____ and _____.
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muscle strength and abilities
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If a patient with MG has dysphagia, medications may be given _____.
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parenterally
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Patients with MG who are taking anticholinesterase meds should always have _____ available in case of respiratory distress.
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Muscarinic antagonist
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On of the most serious problems of anticholinesterase medications is ______.
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respiratory distress
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A ______ is a result of an overdose with anticholinergic medication.
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cholinergic crisis
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A ____ is a sudden exacerbation of motor weakness caused by under medication.
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myasthenic crisis
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S/Sx of cholinergic crisis are
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-GI manifestation
-severe muscle weakness -vertigo -respiratory distress |
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S/Sx of myasthenic crisis are:
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-tachycardia
-tachypnea -severe respiratory distress -dysphagia -impaired speech -anxiety |
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To distinguish between myasthenic crisis and cholinergic crisis, _____ is used.
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Tensilon test
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