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21 Cards in this Set
- Front
- Back
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What is the pathology of cervical dysplasia and carcinoma in situ?
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Disordered epithelial growth, begins at basal layer of squamo-columnar junction @ cervix
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What are the 3 classifications of cervical dysplasia and carcinoma in situ?
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CIN 1-3, depending on the extent of dysplasia
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What 2 HPV genes are associated with CIN?
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HPV 16 and 18
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What are the risk factors for cervical carcinoma?
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Multiple sex partners, smoking, early sexual intercourse, HIV
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What is the most common pathology of invasive carcinoma?
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Squamous cell carcinoma
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What is the pathology of endometritis?
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Inflammation of the endometrium with retained products of conception following delivery
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How do you treat endometritis?
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Gentamycin + clindamycin w/ or w/out ampicillin
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What is the pathology of endometriosis?
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Non-neoplastic endometrial glands/stroma in abnormal locations outside the uterus
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What are the characteristics of endometriosis?
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Cyclic bleeding from ectopic endometrial tissue resulting in blood-filled chocolate cysts
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What is the treatment for endometriosis?
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OCP, NSAID's, leuprolide, danazol
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What is the pathology of Adenomyosis?
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Endometrium within the myometrium
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How do you treat Adenomyosis?
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Hysterectomy
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What is the difference between endometriosis and adenomyosis?
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Uterus is normal sized in endometriosis and uterus is enlarged in adenomyosis
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What is the pathology of endometrial hyperplasia?
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Abnormal endometrial gland proliferation usually caused by excess estrogen stimulation
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How does endometrial hyperplasia usually present?
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Postmenopausal vaginal bleeding
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What are some risk factors for endometrial hyperplasia?
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Anovulatory cycles, HRT, polycystic ovarian syndrome, granulosa cell tumor, estrogen secreting tumor
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What is the pathology of endometrial carcinoma?
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MOST COMMON GYNECOLOGICAL MALIGNANCY
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What is the typical presentation of endometrial carcinoma?
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Vaginal bleeding
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What is endometrial carcinoma preceeded by?
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Endometrial hyperplasia
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What are some risk factors for endometrial carcinoma?
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Prolonged use of estrogen without progestins, DM, HTN, nullparity, late menopause
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What worsens the prognosis of endometrial carcinoma?
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Increased myometrial invasion
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