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24 Cards in this Set
- Front
- Back
1st step in treating pts with neuro probs?
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localize lesion
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sx of myopathies?
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prox symmetrical weakness w/o sensory loss
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what sx do nmj diseases cause?
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fatigability
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what sx are caused by peripheral neuropathies?
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distal asymmetric weakness with atrophy, fasciculations, sensory loss and pain
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what sx are caused by radiculopathies?
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radiating pain
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sx caused by spinal cord disease?
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triad of distal symmetric weakness, sphincter probs, and a sensory level
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what causes 'crossed syndromes' and what are they?
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unilateral brain stem lesion; ipsilateral dysfunction of a cranial nerve accompanied by hemiparesis and/or hemisensory loss on contralateral body
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what type of problem causes ataxia and action tremor?
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cerebellar disease
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in general what type of lesions cause aphasia, seizures and partial hemiparesis (face, arm only)?
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cortical lesion
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what type of problems are caused by subcortical lesions?
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visual field cuts, dense numbness of primary sensory modalities and more complete hemiparesis (face, arm, leg)
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what is long-term potentiation?
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repetitive input to a synapse leads to learning and memory
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which neurotransmitter is related to each condition:
1. Alzheimer's 2. epilepsy 3. Parkinson's 4. migraine |
1. acetylcholine
2. gamma-aminobutyric acid, or GABA 3. dopamine 4. serotonin |
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what is a characteristic pattern (in DNA) of several neuro diseases?
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trinucleotide repeats
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give two possible reasons for foot drop (weakness of tibialis anterior muscle)
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1. lesion to the common peroneal nerve
2. lesion to the L5 root |
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sx if facial nerve is damaged (eg. Bell's Palsy)?
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entire face is weak
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sx if cortical input to facial nerve is damaged (eg. stroke)?
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lower half of face is weak
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what does dilated or "blown" pupil imply?
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compression of CN III
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what is a natural protector against strokes in the brain?
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collateral blood flow from the Circle of Willis
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is non-communicating hydrocephalus a medical emergency?
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yes - blockage will cause increase in CSF and thus ICP
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name 3 tests to help diagnose myopathies
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serum creatinine kinase (CK) levels, electromyography (EMG) and muscle biopsy
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what is the most common muscular dystrophy in adults?
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myotonic dystrophy
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what is a big concern in the treatment of pts with myopathies?
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respiratory failure
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what should always be included in the DDX of myopathies?
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drug toxicity
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is neuroleptic malignant syndrome a medical emergency?
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yes and it has a high mortality
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