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38 Cards in this Set
- Front
- Back
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385. All of the following are true of mRNA EXCEPT one. What is the exception?
A. mRNA is single-stranded B. There is a separate mRNA encoded for each amino acid C. mRNA is synthesized in the nucleus of eukaryotic cells D. mRNA is complimentary to one strand of DNA E. mRNA is translated during protein synthesis |
There is a separate mRNA encoded for each amino acid
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386. Synthesis of tRNA requires
A. transcription, but not translation B. translation, but not transcription C. transcription and translation D. the presence of a primer chain of DNA E. messenger RNA |
transcription, but not translation
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387. Comparing RNA to DNA synthesis,
A. DNA synthesis requires more proteins than does RNA synthesis B. DNA synthesis requires RNA, and RNA synthesis requires DNA C. DNA synthesis is initiated on single-stranded DNA, while RNA synthesis is initiated on double stranded DNA D. The number of purines is equal to the number of pyrimidines in a length of double stranded DNA, but this need not be the case for RNA E. All of the above are correct |
All of the above are correct
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388. Messenger RNA
A. is the most abundant form of RNA in cells B. is synthesized by RNA polymerase III C. synthesis is blocked by α-amanitin D. is the smallest of all RNAs E. has about 90% common sequences from one mRNA to another mRNA |
synthesis is blocked by α-amanitin
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389. Initiation of transcription
A. is encoded by a DNA sequence in a Hogness Box in eukaryotes B. occurs at the promoter site of the operon C. occurs only after the initiation site is methylated D. All of the above E. A and B, but not C |
A and B, but not C
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390. RNA polymerase differs from DNA polymerase in that it has no exonuclease activity. This isn't a problem because
A. RNA polymerase doesn't make mistakes B. the products of RNA polymerase have limited half-lives, while a mistake in DNA lasts forever C. peptidyltransferase can remove the improper code in the cytoplasm D. it is the job of RNA polymerase I to remove errors following transcription E. repressor proteins bind to, and cover up, any errors in RNA |
the products of RNA polymerase have limited half-lives, while a mistake in DNA lasts forever
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391. Which of the following statements about the operon is INCORRECT?
A. The cyclic AMP-CAP complex binds to the operator site and allows transcription to begin B. The regulator site causes synthesis of repressor protein when RNA polymerase binds to the promoter site C. The inducer for transduction binds to the repressor protein and allows RNA polymerase to move along DNA D. Transcription factors can bind to DNA near promoter sites and enhance binding of RNA polymerase E. All of the above are correct |
The cyclic AMP-CAP complex binds to the operator site and allows transcription to begin
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392. Which of the following antibiotics acts by inhibiting mRNA synthesis?
A. Streptomycin B. Tetracycline C. Actinomycin D. Erythromycin |
Actinomycin
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393. During synthesis of mRNA
A. the sense strand is read from the 5' to the 3' end B. the sense strand is stabilized by emerging mRNA C. the DNA strands are uncoiled by helicase D. the anti-sense strand is read from the 3' to the 5' end E. All of the above are correct |
the anti-sense strand is read from the 3' to the 5' end
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394. RNA synthesis is terminated by
A. rho proteins B. base-pairing of RNA nucleotides to neighboring portions of the RNA molecule C. degradation of RNA polymerase D. All of the above are used to terminate transcription E. A and B, but not C |
A and B, but not C
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395. If the enzymes contained in splicosomes are inhibited, you would expect that
A. intron fragments would increase B. exon fragments would increase C. subsequenctly synthesized proteins would be non-functional D. repressor proteins would rapidly be made in order to save energy E. All of the above would be expected |
subsequenctly synthesized proteins would be non-functional
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396. Inhibition of ____________ will result in fewer ribosomes in the cell.
A. RNase P B. RNase D C. RNase III D. A site of the ribosome E. P site of the ribosome |
RNase III
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397. During transcription
A. DNA is made from a DNA template B. RNA is made from a DNA template C. RNA is made from an RNA template D. Protein is made from an RNA template E. Protein is made from a DNA template |
RNA is made from a DNA template
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398. How many high energy phosphate bonds are hydrolyzed during the synthesis of a single codon for an amino acid during transcription?
A. 2 B. 3 C. 4 D. 5 E. 6 |
6
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399. The Pribnow box is located here:
A. Promoter site B. Operator site C. RNA Polymerase I D. RNA Polymerase III E. Exon |
Promoter site
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400. An inducer binds here:
A. RNA Polymerase I B. Repressor protein C. Promoter site D. Operator site E. Exon |
Repressor protein
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401. Which of the following is stabilized by RNA Polymerase II?
A. Sense strand B. Antisense strand C. Exon D. Intron E. Promoter site |
Sense strand
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402. Which of the following is stabilized by RNA Polymerase II?
A. Sense strand B. Antisense strand C. Exon D. Intron E. Promoter site |
Sense strand
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403. Which of the following is present in a splicosome?
A. Repressor protein B. Operator site C. Promoter site D. Exon E. Sense strand |
Exon
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404. Which of the following produces hnRNA?
A. RNA Polymerase I B. RNA Polymerase III C. Repressor protein D. DNA Polymerase I E. None of the above |
None of the above
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405. Eukaryotes require transcription factors to be bound here to initiate transcription:
A. Operator site B. Promoter site C. Regulatory site D. Exon E. Intron |
Promoter site
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406. Which of the following makes messenger RNA?
A. DNA polymerase I B. RNA polymerase I C. RNA polymerase II D. RNA polymerase III E. Reverse transcriptase |
RNA polymerase II
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407. The promoter site.
A. Is recognized by the sigma subunit of polymerase. B. Precedes the operon. C. Is present only for those genes that are expressed by a specific cell. D. Encodes for synthesis of repressor proteins. E. All of the above |
Is recognized by the sigma subunit of polymerase.
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408. Which statement is FALSE?
A. During transcription, polymerase reads the antisense strand of DNA. B. mRNA is written from the 5' end to the 3' end. C. The sense strand of DNA is stabilized by polymerase during transcription. D. A poly-A tail destabilizes the emerging hnRNA during transcription, aiding in termination. E. Rho proteins hydrolyze ATP and may assist in termination of transcription. |
A poly-A tail destabilizes the emerging hnRNA during transcription, aiding in termination.
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409. Post-transcriptional processing
A. Takes place in splicosomes B. Includes removal of introns. C. Includes methylation of guanine on the 5' end of the RNA D. All of the above. E. A and B, but not C |
All of the above.
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410. The promoter site
A. Is located immediately after the Hogness Box B. Immediately precedes the operon C. Contains a TATA sequence in a G-C rich region D. Is inhibited by repressor proteins E. "Promotes" transcription of the sense strand. |
Contains a TATA sequence in a G-C rich region
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411. During transcription,
A. The sense strand is stabilized by RNA polymerase B. The antisense strand is read from 5' to 3' C. The formation of a hairpin turn helps maintain transcription. D. mRNA is made directly. E. Introns and exons are both synthesized, with exons to be removed later. |
The sense strand is stabilized by RNA polymerase
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412. RNA polymerase II synthesizes
A. tRNA B. rRNA C. mRNA D. All RNAs, using DNA as a template E. All RNAs, using RNA as a template |
mRNA
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413. Premature termination codes
A. Are palindromic sequences followed by a poly-U "tail" B. Are present only in the nuclear DNA of cells which will not express the protein C. Require the presence of a stabilizing protein for full transcription D. Result from intron ambiguity E. Are activated when phosphorylated |
Require the presence of a stabilizing protein for full transcription
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414. Which of the following is INCORRECT regarding RNA polymerase?
A. It reads from 3' -> 5' B. It writes from 5' -> 3' C. It requires double-stranded DNA as a template D. It contains 3' -. 5' exonuclease activity E. It produces phosphodiester bonds |
It contains 3' -. 5' exonuclease activity
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415. A Pribnow Box
A. Is found in prokaryotes B. Contains a TATA sequence C. Is part of the promoter site D. Is recognized by the σ subunit of RNA polymerase E. All of the above |
All of the above
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416. Which of the following is NOT a part of the operon?
A. Gene B. Operator site C. Regulator site D. Promoter site E. All of the above are part of the operon |
All of the above are part of the operon
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417. During transcription
A. The sense strand is transcribed B. The non-template strand is stabilized by single stranded binding protein C. Termination occurs at the stop codon D. A rho protein may assist termination E. All of the above |
A rho protein may assist termination
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418. Which of the following statements is CORRECT?
A. If you pulled double-stranded DNA apart, one strand would be the sense strand, and the other the antisense strand B. Exons are removed from hnRNA and introns spliced to form mRNA C. The final mRNA produced by transcription contains a poly-U tail D. Small nuclear ribonucleoprotein particles (snRNPs) are found in splicosomes E. snRNA is the portion of hnRNA which is not included in the final mRNA product |
Small nuclear ribonucleoprotein particles (snRNPs) are found in splicosomes
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419. You would find a Pribnow Box
A. At the Promoter site B. As the primary catalytic unit of DNA polymerase C. In the transcript unit of a gene D. At the Operator site E. At the Regulator site |
At the Promoter site
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420. During the elongation phase of transcription
A. The RNA transcript can be found at the P site B. The antisense strand acts as the template for transcription C. The non-template strand is stabilized by single stranded binding protein D. The template strand is read from 5' to 3' E. All of the above |
The antisense strand acts as the template for transcription
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421. Post-transcriptional processing
A. Converts mRNA into hnRNA B. Includes carboxylation of the 5' end of the transcript C. Includes addition of a poly-U tail to the transcript D. Requires the use of small nuclear ribonucleoprotein particles (snRNPs) E. Involves the splicing together of introns |
Requires the use of small nuclear ribonucleoprotein particles (snRNPs)
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422. Which of the following is INCORRECT?
A. In replication, read 3' to 5', write 5' to 3' B. In mRNA synthesis, read 3' to 5', write 5' to 3' C. In rRNA synthesis, read 3' to 5', write 5' to 3' D. In translation, read 5' to 3', write 3' to 5' E. All of the above are correct |
In translation, read 5' to 3', write 3' to 5'
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