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13 Cards in this Set
- Front
- Back
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1. Which of the following antibiotics acts by inhibiting mRNA synthesis?
A. Streptomycin B. Tetracycline C. Actinomycin D. Erythromycin |
Actinomycin
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2. The sequence CCCGGG in a portion of a mother strand of DNA has become CCTGGC two generations later. Which of the following probably occurred?
A. Transition B. Transversion C. Deletion D. Insertion E. More than one of the above |
More than one of the above
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3. Which of the following would theoretically help relieve the symptoms of gout?
A. Increase xanthine oxidase activity B. Inhibit uric acid excretion C. Inhibit adenosine kinase D. Activate adenine phosphoribosyl transferase E. Facilitate conversion of hypoxanthine to xanthine |
Activate adenine phosphoribosyl transferase
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4. Which of the following would you expect to see in a patient after they begin taking allopurinol?
A. Uric acid levels in their urine would decrease B. Adenylosuccinate synthetase and IMP dehydrogenase activity would probably be decreased indirectly C. Xanthine levels would tend to increase D. Malonate levels in urine would NOT be affected E. All of the above would be expected |
All of the above would be expected
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5. Mutations.
A. Can result from the transition of one purine to another. B. Can result from the transversion of a purine for a pyrimidine C. May be caused by hydroxylamine altering cytosine structure D. May result from insertions produced by acridines E. All of the above are correct. |
All of the above are correct.
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6. Which of the following would be effective in treating a procaryotic infection?
A. Streptomycin B. Tetracycline C. Puromycin D. Erythromycin E. All of the above. |
All of the above.
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7. Gout can be effectively treated with
A. Aspirin B. Haloperidol C. Allopurinol D. Urea E. Uric acid |
Allopurinol
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8. Ultraviolet light exposure damages DNA by
A. dimerizing thymine B. converting guanine to adenine C. substitution of purines for pyrimidines D. unwinding of the double helix E. conversion of adenine to uracil |
dimerizing thymine
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9. A mutation which results in an adenine in place of a guanine in future generations is an example of
A. Transition B. Transversion C. Insertion D. Interference E. UV dimerization |
Transition
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10. A mutation which alters the DNA code from UGG to UGA is called a
A. Silent mutation B. Missense mutation C. Nonsense mutation D. Transversion E. Wobble |
Nonsense mutation
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11. Allopurinol is used to treat gout because it
A. Stimulates adenine phosphoribosyl transferase (APRTase) B. Inhibits adenosine kinase C. Inhibits GPRTase D. Inhibits xanthine oxidase E. Stimulates thioredoxin reductase |
Inhibits xanthine oxidase
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12. Which of the following is particularly dangerous because it leads to a frameshift?
A. Transition B. Transversion C. Insertion D. Exposure to alkylating agents (like mustard gas) E. Exposure to 5-bromouracil |
Insertion
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13. A "point" mutation during transcription
A. Can be a silent mutation, especially if it is in the third position of a codon B. Can be a nonsense mutation if UGG is converted to UGA C. Is less dangerous than a point mutation during replication D. Is more likely to occur than during replication, because RNA polymerase contains no exonuclease activity E. All of the above are correct |
All of the above are correct
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