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88 Cards in this Set
- Front
- Back
2 major morphological divsions of the NS:
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1. CNS
2. PNS |
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What is the CNS composed of?
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Brain + Spinal Cord
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What is the PNS composed of? (3 things)
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CNS fiber outflow
Sensory fiber inflow Peripheral ganglia |
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What structures are found in the CNS?
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-Cell bodies/major process of the Brain, Spinal Cord, and Interneurons
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What structures are found in the PNS?
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-Afferent neurons projecting into the CNS
-Efferent neurons projecting out of the CNS |
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2 Major FUNCTIONAL divisions of the PNS:
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1. Somatic nervous system
2. Autonomic nervous system |
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What does Somatic mean?
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That the somatic axons innervate skeletal muscle (either motor or sensory).
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What does Autonomic mean?
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That the axons innervate
-Smooth muscle -Cardiac muscle -Glands -GI neurons |
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Where somatic efferents/afferents cause changes in the external environment, what do Autonomic Efferents/afferents do?
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Cause and sense changes in the body's internal environment
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What is the ANS derived from?
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Neural Crest
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Does neural crest only give rise to the ANS?
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Obviously no, it gives rise to many things.
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What determines the fate of neural crest cells?
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Their axial level
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What does neural crest at the Cranial spinal cord level give rise to?
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Parasympathetic ganglia
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What does neural crest at the Vagal spinal cord level give rise to?
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-Enteric ganglia
-Parasympathetic ganglia -Superior cervical ganglion |
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What does neural crest at the Trunk spinal cord level give rise to?
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-Sympathetic ganglia
-Adrenal medulla |
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What does neural crest at the Lumbosacral spinal cord level give rise to?
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-Enteric ganglia
-Parasympathetic ganglia |
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3 divisions of the ANS:
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-SNS
-PNS -ENS |
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What does the SNS function to do?
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Equips the body for intense muscular action required in offense and defense
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What does the PNS function to do?
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Restore and conserve energy and give rest to vital organs.
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What does the ENS function to do? (4 things)
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1. Regulate enteric secretions
2. Renerate intestinal epithelium 3. Contract smooth muscles 4. GI motility |
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How is the ENS related to the PNS and SNS?
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It can operate independently, but is modulated by SNS and PNS fibers.
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At what spinal cord levels are SNS preganglionic neurons?
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T1-L2
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At what spinal cord levels are PNS preganglionic neurons?
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-Brainstem nuclei
-S2-S4 |
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Where are the Enteric preganglionic neurons found?
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In the walls of the gut
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What is the cell column in the SC that houses SNS/PNS pregang. neurons?
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Intermediolateral cell column
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How are pre- and postganglionic neurons different in both the SNS and PNS?
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Pre = myelinated
Post = unmyelinated |
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Where do preganglionic neurons synapse on postganglionics?
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At clusters of cell bodies called GANGLIA
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What type of ANS input do most organs recieve?
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Input from both SNS and PNS, which is usually opposing.
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What organs recieve parallel (both excitatory) input from the SNS and PNS?
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Salivary glands
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8 Responses included in a Sympathetic outflow increase:
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-Increased heartrate
-Increased blood pressure -Increased Cardiac output -Diversion of bloodflow from skin to skeletal muscle -pupil dilation -Bronchiolar dilation -Sphincter contraction -Mobilization of fat/glycogen |
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How are ganglia of the SNS situated relative to the spinal cord?
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Close to it and in chains
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How are ganglia of the PNS situated relative to the spinal cord?
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Far from it - ganglia are within or close to target organs.
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4 Primary Things that happen during a PNS outflow increase:
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-Reduced heartrate
-Reduced blood pressure -Digestion/nutrient absorption -Waste excretion |
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What is another name for the interomediolateral cell column that houses s2-S4 PNS neurons?
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SPN - sacral parasympathetic nucleus
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What is the effect of SNS vs PNS action on the Eye?
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SNS = dilates pupil
PNS = constricts pupil |
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What is the effect of SNS vs PNS action on the Lacrimal gland?
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PNS stimulates lacrimation
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What is the effect of SNS vs PNS Salivary glands?
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SNS = viscous secretion
PNS = watery secretion |
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What stimulates sweat glands?
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SNS
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What is the effect of SNS vs PNS action on the lungs??
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SNS = bronchial relaxation
PNS = bronchoconstriction |
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How does the SNS affect Vascular smooth muscle? (Skin vs muscle)
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Skin vessels = contracts
Muscle vessels = relax |
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How does the PNS affect all vascular smooth muscle?
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Dilates
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What is the effect of SNS vs PNS action on the GI tract?
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SNS: relax muscle walls, contract sphincters, decrease motility
PNS: opposite |
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What is the effect of SNS vs PNS action on the Bladder and Bladder Sphincter??
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SNS: slight relaxation of the bladder, constricts sphincter.
PNS: contraction of bladder, relaxation of sphincter. |
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What is the effect of SNS vs PNS action on the penis and seminal vesicles?
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SNS: ejaculation
PNS: erection (point and shoot) |
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What efferents found exiting the spinal cord belong to the ANS?
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ALL of them except those innervating skeletal muscle!
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So what type of system is the ANS predominantly?
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An efferent motor system of general Visceral Efferents - GVE
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What are most of the GVAs concerned with?
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Mediation of visceral sensation and regulation of vasomotor and respiratory reflexes - PNS
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What GVA axons carry sensations from baro/chemoreceptors in the heart? To where?
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cn IX and X - to the brainstem (NTS)
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What carries GVA fibers from the gut to the CNS?
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-Vagus nerves
-Splanchnic nerves -Pelvic nerves |
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What carries pain fibers from blood vessels?
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Somatic nerves
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What happens once afferents from bloodvessels, heart and viscera reach the brain?
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They elicit reflex responses through efferents.
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General nature of ANS reflexes:
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-Involuntary
-Unconscious |
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GVEs transmit impulses from ___ to ____:
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From CNS to peripheral systems.
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Where are visceral motor responses elicited?
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In smooth muscle and glands
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What is the main difference in the ANS compared to somatic in terms of how its targets are stimulated?
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It uses 2 groups of neurons (SNS and PNS) instead of one.
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Where are the Preganglionic neurons for the ANS housed?
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in the CNS
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Confirm whether the SNS chain ganglia are in the CNS or PNS
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ok
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Where do preganglionics project to?
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Ganglia (paravertebral, prevertebral, etc) where they synapse with postganglionics
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Where do postganglionics go?
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To the target organ
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What are postganglionics called? Are they in the CNS or PNS?
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Motor neurons - in the PNS; so autonomic ganglia lie in the peripheral NS too.
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Where are the autonomic ganglia found?
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-Sympathetic paravertebral chain
-Symp Collateral ganglia (prevertebral) -Parasymp Intramural ganglion |
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Where are the cell bodies of SNS preganglionic neurons found?
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In the intermediolateral horns of SC segments T1-L2
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What is the special name for the spinal cord output from SNS at T1-L2?
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Thoracolumbar outflow
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Where do the paravertebral sympathetic chains extend?
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From cervical to sacral SC levels - so longer than the actual cell bodies in the cord.
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What is achieved by the sympathetic chains being longer than the levels of cell bodies?
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Divergance - 1 cell body can give 10 postganglionic fibers, and these can reach other parts of the body.
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What is the general configuration of the SNS pre and post fibers?
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PRe = short
Post = long |
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Where do Preganglionic SNS fibers exit the spinal cord?
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Out the ventral horn
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Where do SNS preganglionics go after exiting the ventral horn?
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To the mixed root, then branch off as white rami communicantes which can do one of 3 things.
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What are the 3 alternatives available to white rami communicantes?
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1. Synapse within the chain
2. Pass up or down to another level to synapse 3. Pass through and go to a prevertebral ganglion |
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What are the prevertebral nerves that pass thru without synapsing in the paravertebral chain?
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Splanchnic nerves
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What are gray rami for?
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These are the unmyelinated postganglionic fibers that carry the nerve impulse from chain ganglion to target organ.
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Where are white rami found? Where are gray rami found?
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White: only T1-L2 levels
Gray: at every level |
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Why is the sympathetic chain longer than T1-L2?
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So that it can give innervation to the head/neck/lower abdomen, not just the thorax.
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What are the SC levels at which Splanchnic nerves originate?
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T5-T12
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Where do Splanchnic nerves synapse?
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At the Celiac and Superior mesenteric ganglia
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What carries postganglionics from the Celiac / Sup mesenteric ganglia to the target organs?
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Plexuses
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What spinal cord levels give rise to lower Splanchnic nerves that innervate the inferior mesenteric ganglion and hypogastric plexuses?
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T10-L1
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What is the special name for preganglionic parasymp outflow?
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Craniosacral
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Where does the cranial and sacral PNS outflow originate?
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Cranial: In the motor nuclei of cranial nerves 3, 7, 9, and 10
Sacral: in S2-S4 |
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Where are the sacral outflow preganglionic PNS fibers' cell bodies housed? Where do they exit the spinal cord?
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In the intermmediolateral cell column - exit via the ventral horn.
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Where does the craniosacral PNS outflow go?
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To the ganglion that is situated close to the target organ
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So what is the general arrangement of the 2-neuron system for PNS outflow?
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Pre = long
Post = short |
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What are autonomic plexuses?
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Networks of nerves that redistribute SNS and PNS nerves
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What does the hypogastric plexus innervate?
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Most of the large intestine and abdominal and genital organs
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What forms the Cardiac plexus?
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-Cardiac sympathetic nerves
-Vagus nerve branches |
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What forms the Pulmonary plexus?
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-Upper thoracic SNS nerves
-Vagus nerve branches |
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What forms the Celiac plexus?
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-SNS fibers from celiac ganglia and thoracic aortic plexus
-PNS fibers from vagus via the esophageal plexus |
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You know about the enteric nervous system
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right
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