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8 Cards in this Set

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  • Back
What is pathology?
the study of the nature of disease including the pathogenesis, which is the sequence of events causing a disease to manifest.
What is the difference between Anatomic Pathology and Clinical Pathology?
Anatomic - gross and microscopic evaluation
Clinical - more lab focused techniques like analysis of body fluids, cellular level dx
What four gross elements do Anatomic Pathologists evaluate?
size, shape, consistency, color
What microscopic techniques do Anatomic Pathologists use?
1) H&E staining
2) histochemical staining to look for specific cells or elements
3) immunohistochemical stains (Ab stains) to see what structures certain Abs will bind
4) immunofluorescence
5) TEM (transmission electron)
6) molecular techniques
What is the microscopic gold standard?
H&E stains
Define the following: TP (true positive), FP, TN, FN.
TP - people w/ disease w/ + test
FP - people w/o disease w/ + test
TN - people w/o disease w/ - test
FN - people w disease w/ - test
Sensitivity
percent of patients w/ disease whom test positive
Sensitivity = 100*TP/(TP+FN)

Ideally high
Specificity
percent of patients w/o disease whom test negative
Sensitivity = 100*TN/(TN+FP)