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27 Cards in this Set

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Sporotrichosis transmission/infection and demographic
cuts or lesions on hands or arms is most common from soil, tree bark, garden plants and frequent in male gardeners, farmers in Mexico, Brazil, Uruguary, S. Africa
Sporotrichosis post infection presentation
papules as site of infection, spreads through lymphatics, will eventually manifest as (lymphocutaneous) lesions on the skin that follow lymphatics pattern
Sporotrichosis causative agent
Sporothrix schenkii, thermally dimorphic w/ 37C - round yeast, 25C septate hyphae, rosette shaped clusters of conidia at tips of conidiophores
Sporotrichosis Dx
Microscopy of pus or sputum, *Asteroid bodies in histo biopsy within yeast cells and Splendore-Hoeppli, culture, serology
Sporotrichosis Tx
spontaneous, topical/oral (potassium iodide)
Sporotrichosis rare presentation
pulmonary, osteoarticular, disseminated
Chromoblastomycosis transmission/infection and demographic
Caused by trauma (splinters, thorns), in men in tropical/subtropical regions, affecting extremities
Chromoblastomycosis rare presentation
systemic
Chromoblastomycosis post infection presentation
1)cauliflower nodular lesions
2)plaques, central healiing with atrophic yellow scar tissue
Chromoblastomycosis causative agent
Fonsecaea (F. pedrosoi), Cladosporium (C. carrionii)
Chromoblastomycosis Dx
KOH microscopy with sclerotic cells/bodies, velvety culture
Chromoblastomycosis Tx
antifungal tx, surgery, cryosurgery
Mycetoma transmission/infection and demographic
trauma infection of trunk, feet usually from walking barefoot, mainly in men of subcutaneous tissue and bone, more frequent in tropical and subtropical climates
Mycetoma post infection presentation
painless swelling, thickening of skin -> enlarge to become tumorous -> discharge viscous fluid containing GRAINS
Mycetoma causative agents
40% Eumycetoma (Pseudodallescheria boydii (US), Madurella mycetomatis (WW)), Actinomyces
Mycetoma Dx
Clinical triad: tumefaction, draining sinuses, granules. Granules are the most significant
Mycetoma Tx
Surgical antifungal combo, 80% recurrance with surgery
Mycetoma rare presentation
can spread to bone, muscle, blood vessels
Phaeohypomycosis transmission/infection and demographic
saprophytes cause infection, presents on hands and feet, sometimes looks like a synovial cyst, firm or fluctuant to touch, painless
Phaeohypomycosis post infection presentation
cyst, can spread to face and trunk, hyperpigmented demarcated plaques
Phaeohypomycosis causative agent
over 20 saprophytes, but remember Exophilia jeanselmei and Wangiella dermtitidis
Phaeohypomycosis Dx
Microscopy w/ brown pigmented, branching septate hyphae and dark walled yeast, histo with hyphae with giant cells
Phaeohypomycosis Tx
surgical, antifungal
Zygomycosis transmission/infection and demographic
traumatic implantation
Zygomycosis causative agent
C. coronatus in males' nasal submucosa; B. ranarum in male children's limbs, trunk
Zygomycosis Dx
Biopsy, so histo necessary: focal clusters of inflammation eosinophils and zygomycotic hyphae - Splendore-Hoeppli phenomenon
Zygomycosis Tx
Surgery, anti-fungal (itraconazole, oral potassium iodide)