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9 Cards in this Set
- Front
- Back
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leishmaniasis common name
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Leishmaniasis
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leishmaniasis causal agent
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Leishmania tropica - L. mexicana - Mastigophora (flagellates)
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leishmaniasis reservoir & transmission
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zoonoses - sand fly salivory gland harbors infections stage - transmitted through bite - vector: phlebotomine flies require blood to produce mature eggs - reservoir: flies, wild & domestic animals (dogs) humans(accidental hosts)
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leishmaniasis portals of entry/exit - toxin -virulence factor - area affected
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local infection of skin capillaries
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leishmaniasis signs & symptoms
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single red papule at bite site - spreads laterally to an ulcer - Systemic: intermittent fever - weight loss - enlarged spleen, liver, lymph nodes
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leishmaniasis lab id
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detected in cutaneous lesion or bone marrow during visceral disease - cultivating the parasite - serological tests - leishmanin skin testing
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leishmaniasis treatment
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chemotherapy with injected pentavalent antimony is usually effective - pentamidine or amphotericin B (in resistant cases)
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leishmaniasis prevention
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application of insecticides & eliminating sand fly habitats - vaccine based on recombinant DNA technology still under development
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leishmaniasis other information
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endemic to equatorial regions - over 50 sand fly species
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