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4 Cards in this Set
- Front
- Back
Aminoglycosides - mode of action
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Bactericidal - binds to ribosomes
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Examples of aminoglycosides
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Amikacin, gentamicin, neomycin, streptomycin and tobramycin
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Aminoglycoside - uses
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Bactericidal against some gram-positive and many gram-negative. Amik, gent and tobra also active against Pseudomonas, streptomycin - TB.
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Aminoglycosides -side effects
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Ototoxic, nephrotoxic - occur mostly in children and renal failure. Rash with streptomycin, hypomagnesaemia on prolonged therapy
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