Postural Orthostatic Tachycardia Syndrome

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POSTURAL = position of the body
ORTHOSTATIC = relating to or caused by an upright posture
TACHYCARDIA = increased heart rate
SYNDROME = a combination of symptoms

Normally, when a person stands up, the heart rate increases by 10 beats per minute or less. With POTS, the increase is often far greater - usually 30 beats per minute or more.

Postural orthostatic tachycardia syndrome is a condition in which a change from the supine position to an upright position causes an abnormally large increase in heart rate, called tachycardia.
When an adult without POTS stands up, gravity pulls blood into the lower body
The brain senses a sudden loss of blood and triggers a response (heart beats faster, heart beats with greater force)
Vessels in lower half
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The brain still sensing the loss of blood, maintains the rapid heartbeats & abnormal blood pressure. Often times this leads to fainting or lightheadedness.
Orthostatic Intolerance describes a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position.
Postural Orthostatic Tachycardia Syndrome (POTS) is a form of Dysautonomia (estimated to impact between 1,000,000 and 3,000,000 Americans, & millions more world wide)

Dysautonomia is an umbrella term for various conditions in which the autonomic nervous system (ANS) does not work correctly.
Dysautonomia is a type of neuropathy affecting the nerves that carry information from the brain and spinal cord to the heart, bladder, intestines, sweat glands, pupils, and blood vessels.
People living with various forms of Dysautonomia have trouble regulating these systems which can result in lightheadedness, fainting, unstable blood pressure, and abnormal heart rates, like in the case of
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Eating too much refined carbohydrates
Speed of positional change - don't stand up to quickly
Dehydration
Time of the day (symptoms may be worse in the morning upon rising)
Menstrual period
Prolonged bed rest
Alcohol (dilates the blood vessels)
Exercise (initial start of exercise may make symptoms worse, but with time ongoing exercise will improve symptoms

or a heart rate that exceeds 120 bpm (tachycardia), within 10 minutes of rising
Patients are usually diagnosed by a Cardiologist or Neurologist
Therapies for POTS are targeted at relieving low blood volume or regulating circulatory problems that could be causing the disorder
No single treatment has been found to be effect for all
A number of drugs seem to be effective in the short term
Beta Blockers - used to control heart rhythm & reduce high blood pressure)
Alpha Agonists - narrow blood vessels & help push back more blood to the heart
SSRI's & SNRI's - serotonin plays a part in control of both heart & blood pressure
Fludrocortisone - synthetic steroid makes person retain salt & produces increase in blood volume
Desmopressin - hormone reduces urine production, promotes water retention & increase heart rate
Erythropoietin - increases amount of red blood cells & increases blood

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