Myelodysplastic Syndrome Research Paper

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Myelodysplastic syndromes, also known as MDS and pre-leukemia, are a group of disorders caused when the production of white blood cells, red blood cells, or platelets is interrupted (Myelodysplastic Syndrome Treatment 2016). These syndromes are rare, fewer than 14,000 cases of myelodysplastic syndromes occur in the United States each year (Statistics about Myelodysplastic syndromes). Blood cells and bone marrow do not fully develop or become mature enough to function properly when a person has myelodysplastic syndromes. Blood cells not becoming mature can cause many problems. If the white blood cells, the blood cells that fight infection, do not work properly infections will be more prevalent. The body of the patient will not be able to fight …show more content…
In refractory cytopenia with unilineage dysplasia the number of one specific type of blood cell is minimal. The blood cells that there are not many of look unusual under a microscope. Refractory anemia with ringed sideroblasts occur when there is a low number of red blood cells. The red blood cells that do exist have ringed sideroblasts. Ringed sideroblasts is an overabundance of iron. Two of the three types of blood cells are unusual in refractory cytopenia with multilineage dysplasia. In the blood stream under one percent of the cells are blasts. Blasts are cells that not fully matured. Either red blood cells, white blood cells or platelets may be at low levels and not look right under a microscope in refractory anemia with excess blasts. Blasts are found throughout the blood. This makes up two types of MDS there are refractory anemia with access blasts types one and two. In the syndrome that is uncommon, myelodysplastic syndrome unclassified, the white blood cells or platelets look abnormal under a microscope. One of the three types of blood cells is lower than normal. Cells with a certain mutation in the DNA along with a small number of red blood cells is myelodysplastic syndrome associated with isolated del chromosome abnormalities (Staff Myelodysplastic Syndrome 2016). Many of the types of MDS can turn into acute myeloid leukemia (Myelodysplastic Syndrome Treatment

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