Mirsky, A. F., Bieliauskas, L. A., French, L. M., Van Kammen, D. P., Jönsson, E., & Sedvall, G. (2000). A 39-year follow-up on the Genain quadruplets. Schizophrenia Bulletin, 26(3), 699-708.
The research in this article is a follow up study on the Genin quadruplets. It revisits questions from the previous research such as the effect of nature and nurture on schizophrenia. The current research asks how genetics and old age effect schizophrenia and expands upon the idea of nature and nurture having on effect on schizophrenia.
The hypothesis for the research was old age has an effect of schizophrenia. The researchers also explored the theory that the quadruplets have an extra band on their 15p chromosome, and nature-nurture interactions on schizophrenia.
The research design used was a combination of case and longitudinal study. The case study was used because it is rare to find identical quadruplets that develop schizophrenia in their twenties. A longitudinal study was used to track how old age and long-term antipsychotic medicine treatment would affect schizophrenia.
Age the tests were taken was the …show more content…
The differing phenotypic expression was thought to have played a part in the severity of schizophrenia experienced by each sister. Brain injury at birth is another possible explanation for the varying levels of schizophrenia experienced by the quadruplets. Nora (the first born) and Hester (the last to be born) were thought to have more experienced more brain damage because they were born first and last respectively. Nora's test scores support this idea, suggesting that she experienced more damage to her prefrontal cortex. Hester's scores also supported this idea, it is speculated that she suffered from more damage to her prefrontal cortex and her brainstem than her other
The research in this article is a follow up study on the Genin quadruplets. It revisits questions from the previous research such as the effect of nature and nurture on schizophrenia. The current research asks how genetics and old age effect schizophrenia and expands upon the idea of nature and nurture having on effect on schizophrenia.
The hypothesis for the research was old age has an effect of schizophrenia. The researchers also explored the theory that the quadruplets have an extra band on their 15p chromosome, and nature-nurture interactions on schizophrenia.
The research design used was a combination of case and longitudinal study. The case study was used because it is rare to find identical quadruplets that develop schizophrenia in their twenties. A longitudinal study was used to track how old age and long-term antipsychotic medicine treatment would affect schizophrenia.
Age the tests were taken was the …show more content…
The differing phenotypic expression was thought to have played a part in the severity of schizophrenia experienced by each sister. Brain injury at birth is another possible explanation for the varying levels of schizophrenia experienced by the quadruplets. Nora (the first born) and Hester (the last to be born) were thought to have more experienced more brain damage because they were born first and last respectively. Nora's test scores support this idea, suggesting that she experienced more damage to her prefrontal cortex. Hester's scores also supported this idea, it is speculated that she suffered from more damage to her prefrontal cortex and her brainstem than her other