• Home Page
  • Importance Of Antibiotic Sensitivity Testing For Antimicrobial Resistance

Importance Of Antibiotic Sensitivity Testing For Antimicrobial Resistance

Improved Essays
Show More
Introduction:

Antibiotic sensitivity testing is used in clinical laboratories to predict the effectiveness or failure of antibiotics in vivo by testing in vitro. The need for antibiotic sensitivity testing is urgent due to the surge of antimicrobial resistant pathogens in recent years. Antimicrobial resistance hinders the prevention and treatment of the infections caused by parasites, bacteria, fungi and viruses. Antimicrobial resistance is the resistance of a pathogen to an antimicrobial that was used to treat any infections caused by that particular pathogen. Antimicrobial resistance is a global problem. Antibiotic resistance hampers the effectiveness of treatments, so people remain infected for much longer therefore increasing the risk …show more content…
The antibiotic resistance traits displayed by resistant pathogens are not naturally eradicated so in some cases a resistance to various antibiotics can be acquired over time. This resistance to multiple antibiotics results in multiple drug resistant pathogens such as multiple drug resistant TB (MDR-TB). Multiple drug resistant pathogens are much more challenging to subdue so further testing and research is needed to identify or to create antibiotics that can kill multiple drug resistant pathogens.

There are many antibiotic sensitivity testing methods used in clinical laboratories today. Each of these testing methods has their own advantages and limitations.
All antibiotic sensitivity testing systems have the same intention. The intention is to predict the effectiveness of antibiotics to see if they can be used therapeutically to treat infections caused by pathogens. The data provided from antibiotic sensitivity testing systems can also be applied as a guideline for chemotherapy, so the testing can result in the identification of drugs that are selectively toxic so using these drugs wont bring more harm to the patient.
Antibiotic testing is divided into automated methods, manual methods, mechanism specific tests and genotypic …show more content…
The automated testing systems are used to reduce technical errors and preparation times. Some examples of automated testing systems are; the Vitek system Biomerieux, the Sensititre ARIS system, the Walk-Away system and the Avantage test system. These automated testing systems provide automated inoculation of cards and interpretation and reading. These systems are quick and convenient and can provide results within hours. The limitation of automated systems is the cost involved in the purchase of the machine and the maintenance of the

Related Documents

  • Superior Essays

    Antimicrobial Agents Against Microorganisms
    • 2232 Words
    • 9 Pages

    Antimicrobial Agents Against Microorganisms

    For instance penicillin is known to be effective against gram positive bacteria including Staphylococcus aureus of which during its activity forms surface protein that binds and leads to the osmotic lysis (Willey et al, 2011 page832). However, there are some emergences of bacteria resistance to penicillin causing pathogenic Staphylococcus aureus infections know as Methicillin – resistant Staphylococcus aureus (MRSA) (Chaitow, 1998) commonly found in hospitals. The results showed that Ciprofloxacin (C) was effective against S. aureus solid proof backing the literature that the drug has capabilities against gram-negative species better than Gram –positive (Heritage et al, 1999).…

    • 2232 Words
    • 9 Pages
    Superior Essays
    Read More
  • Improved Essays

    Analysis Of Cephalosporins
    • 931 Words
    • 4 Pages

    Analysis Of Cephalosporins

    Data of table 2 demonstrates that E.coli strains produced sort of difference in resistance. 310217 type showed resistant to all antibiotics investigated whereas, E. coli strain 704476/2 showed sensitivity to all antibiotics experimented. Table 3. Results (below) for the microbial toxin tests performed on selected bacterial organisms.…

    • 931 Words
    • 4 Pages
    Improved Essays
    Read More
  • Decent Essays

    Antibiotic Resistance: Hunting The Nightmare Bacteria
    • 237 Words
    • 1 Pages

    Antibiotic Resistance: Hunting The Nightmare Bacteria

    Antibiotic Resistance Antibiotic resistance (AR) is where formerly effective medications are having less and less impact on bacteria. The few gram-negative AR resistant bacteria discussed were MERSA resistant staph, KPC, and the NDM1 enzyme with its gene found on 11 different bacterias. Alexander Fleming, founder of the first antibiotic even warned us about this very thing. Now more than ever there is an increasing urgency to find an answer to the growing problem of antibiotic resistance.…

    • 237 Words
    • 1 Pages
    Decent Essays
    Read More
  • Improved Essays

    Chloramphenicol And Rifampicin Essay
    • 627 Words
    • 3 Pages

    Chloramphenicol And Rifampicin Essay

    Resistance to the drug can occur in large bacterial populations where some of the cells are less permeable to the drug however the more relevant form of resistance occurs when bacteria develop the ability to make chloramphenicol acetyl-transferase. This enzyme is encoded for on a plasmid and acts as a virulence factor…

    • 627 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Ventilator Associated Pneumonia
    • 1114 Words
    • 5 Pages

    Ventilator Associated Pneumonia

    Explanation of a microbiological algorithm for Hospital-acquired and Ventilator associated pneumonia. This algorithm is intended to deal with the microbiological aspects of hospital-acquired and ventilator-associated pneumonia. The severity of the illness is important in determining when to collect the diagnostic samples and which antimicrobials to administer due to which organisms are present. There are many prognostic scoring systems used to suggest the severity of the disease in patients e.g., The Therapeutic Intervention Scoring System and the Mortality Predictor Model.…

    • 1114 Words
    • 5 Pages
    Improved Essays
    Read More
  • Superior Essays

    Preventing Mrsa Research Papers
    • 1166 Words
    • 5 Pages

    Preventing Mrsa Research Papers

    CONQUERING ANTIBIOTIC RESISTANCE 1 Conquering Antibiotic Resistance: What is MRSA and the Recent Findings in Circumventing MRSA Mary Hernandez University of Texas Rio Grande Valley CONQUERING ANTIBIOTIC RESISTANCE 2 The genus Staphylococcus is a common inhabitant of the skin and mucous membranes. Staphylococci are organisms that are gram positive clusters or tetrads. They stain purple with the Gram’s stain.…

    • 1166 Words
    • 5 Pages
    Superior Essays
    Read More
  • Decent Essays

    Keratitis Case Studies
    • 431 Words
    • 2 Pages

    Keratitis Case Studies

    4 Due to the side effects of synthetic 86 antimicrobial agents and the emerging increase in 87 bacterial resistance to current antibiotic and other antimicrobial agents, many studies 88 have recently focused on characterization of novel potential antimicrobial…

    • 431 Words
    • 2 Pages
    Decent Essays
    Read More
  • Improved Essays

    What Is The Scientific Context Of The Antimicrobial Susceptibility?
    • 428 Words
    • 2 Pages

    What Is The Scientific Context Of The Antimicrobial Susceptibility?

    Determining whether a bacteria can survive in the presence of any antibiotics is critical in managing infectious diseases in patients. The Antimicrobial Susceptibility test is the most widely recognized test in helping specialists pick which anti-infection agents to give to the patients. The reason for the test is to discover proper anti-toxins for the particular contaminations or illnesses the patient has contracted. A few medications are bactericidal in which the drugs kill the bacteria. Some drugs are bacteriostatic in which the drug stops the division of the bacteria, but does not kill them.…

    • 428 Words
    • 2 Pages
    Improved Essays
    Read More
  • Decent Essays

    Neonatal Sepsis Research Paper
    • 293 Words
    • 2 Pages

    Neonatal Sepsis Research Paper

    At the same time ,increased multidrug resistant organisms make the treatment options fewer and the effective treatment is delayed(patel sj and saiman l 2010) Along with other organisms like klebsiella…

    • 293 Words
    • 2 Pages
    Decent Essays
    Read More
  • Improved Essays

    Why Germs Are Bad
    • 815 Words
    • 4 Pages

    Why Germs Are Bad

    Germs are everywhere. Fortunately, most pose no risks to people. And those that do cause disease usually can be killed with antibiotic drugs. Sometimes, however, harmful bacteria evolve ways to “laugh at” antibiotics — survive as if the poisons were not even there. This so-called drug resistance make infections hard, if not impossible, to treat.…

    • 815 Words
    • 4 Pages
    Improved Essays
    Read More
  • Improved Essays

    Corynebacterium Xerosis Lab Report
    • 1245 Words
    • 5 Pages

    Corynebacterium Xerosis Lab Report

    After the incubation period, the agar containing the antibiotic testing was taken out and if the microbe reacted with the antibiotic, a circle or clearing would appear around the disk containing the antibiotic. The diameter of this circle was then measured and compared with a table found on page 95 of the Microbiology Lab Manual to understand the antibiotics resistance, intermediate and sensitive levels, as they differ for each antibiotic. The numbers on the table in the Microbiology Lab Manual represented whether the microbe was resistant, shown in the light blue color on the graph, intermediate, shown in purple, or sensitive to the antibiotic, shown in the periwinkle color. As shown in figure 1 above, indicated with a yellow line, each antibiotic tested on unknown microbe #7 turned out to be sensitive. The diameters of the cleared out areas were vancomycin: 21mm, erythromycin:…

    • 1245 Words
    • 5 Pages
    Improved Essays
    Read More
  • Improved Essays

    Penicillin And Its Impact On Microbiology
    • 1218 Words
    • 5 Pages

    Penicillin And Its Impact On Microbiology

    The treatment of penicillin is a first line defense encountering some infectious agent that can lead to peril in one 's life. The first line defense is nothing else will do at the time but penicillin. Many physicians perform assessments to check the level of allergy by continuously monitoring the patient after the initial dose(“Penicillin Allergies.”). Another example that shows that there are people allergic to penicillin and that bacteria have formed resistance to penicillin and other antibiotics, penicillin will always be relevant to the studies of Microbiology…

    • 1218 Words
    • 5 Pages
    Improved Essays
    Read More
  • Superior Essays

    Essay On Antibiotic Resistance
    • 1506 Words
    • 7 Pages

    Essay On Antibiotic Resistance

    The health of people and animals are extremely important. ”Antibiotic Resistance refers to bacteria that evolve to the point they are not easily killed by antibiotics” (Dorman N.pag.). Antibiotics in livestock are a crucial part of the livestock industry, but with antibiotic resistance in humans occurring more and more often researchers believe that antibiotics in meat are the leading source of this issue. Although, antibiotics has the issue of resistance, there are more positive sides to the issue than some people think.…

    • 1506 Words
    • 7 Pages
    Superior Essays
    Read More
  • Improved Essays

    Erythromycin Case Study Questions And Answers
    • 1362 Words
    • 6 Pages

    Erythromycin Case Study Questions And Answers

    1. Describe 3 targets of antibiotics, why each target is unique to the particular bacteria, and under what circumstance the bacteria could be resistant to that particular drug. (5 pts) As the name implies 50s subunit protein synthesis inhibitors such as erythromycin inhibit protein synthesis by binding to the 50S subunit of the 23S rRNA molecule of the bacterial ribosome. This ultimately acts to block the exit of the growing peptide chain.…

    • 1362 Words
    • 6 Pages
    Improved Essays
    Read More
  • Great Essays

    Evidence Of Evolution Essay
    • 1222 Words
    • 5 Pages

    Evidence Of Evolution Essay

    Since the 1940,s, antimicrobial drugs, such as antibiotics, have been effectively used to cure patients with infectious diseases. Over time, however, many pathogens have evolved to resist the drugs that were designed to destroy them, making the products increasingly ineffective. This happens because the bacteria adapt to the environment due to natural selection. Then bacteria with the resistant genotype will reproduce and spread. Drug resistant pathogens are linked with the over prescription of antibiotics, as well as missing doses when taking antibiotics.[28]…

    • 1222 Words
    • 5 Pages
    Great Essays
    Read More

Related Topics

Ready To Get Started?
Discover
Company
Follow
©2024 Cram.com
Privacy Policy |  About Ads |  Site Map |  Advertise  | 
  • Cookie Settings