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22 Cards in this Set
- Front
- Back
ACTH stimulates the release of which hormones from the adrenal cortex?
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mainly cortisol and androgens
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What effect will long term, high dose hydrocortisone use have on ACTH levels? Increase, decrease or no change
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decrease
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What effect will long term, high dose hydrocortisone use have on the adrenal cortex? hypertrophy, atrophy or no change
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atrophy
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hydrocortisone has which type of effect? mainly glucocorticoid, mainly mineralocorticoid, or both
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both
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fludrocortisone has which type of effect? mainly glucocorticoid, mainly mineralocorticoid, or both
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mineralocorticoid
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hydrocortisone has which type of effect? raise blood glucose levels or reduce blood glucose levels
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raise
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fludrocortisone has which type of effect? increase Na retention or decrease Na retention by the kidney
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increase Na retention by the kidney
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fludrocortisone has which type of effect? increase K excretion or decrease K excretion by the kidney
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increase K excretion by the kidney
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What is Addison’s disease?
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primary adrenal insufficiency
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What is the main cause of secondary adrenal insufficiency?
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long term glucocorticoid use
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Addison’s disease will mainly decrease the levels of which hormones?
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Cortisol, androgens and aldosterone
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Secondary adrenal insufficiency will mainly decrease the levels of which hormones?
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Cortisol and androgens
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What is the main treatment for Addison’s disease?
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hydrocortisone, fludrocortisone if still hyperkalemic
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What is the main treatment of secondary adrenal insufficiency from a nonfunctioning pituitary?
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hydrocortisone
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What hormonal changes occur with congenital adrenal insufficiency?
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reduced cortisol, aldosterone and elevated androgens
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What effect will congenital adrenal insufficiency have on ACTH levels?
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increase
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What is the main treatment of congenital adrenal insufficiency?
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hydrocortisone
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What happens to endogenous cortisol, androgen and aldosterone levels with hydrocortisone treatment of congenital adrenal insufficiency?
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cortisol and aldosterone stay about the same, androgen levels decrease
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What is the main treatment for an acute adrenocortial insufficiency during surgical procedures?
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hydrocortisone
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What are ACTH levels like with a pituitary adenoma that causes Cushing’s syndrome?
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increased
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In a patient with Cushing’s syndrome, a low dose of dexamethasone will have what effect on endogenous cortisol levels?
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no effect
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What is the main clinical use of mitotane?
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Cushing’s disease
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