Osteogenesis Imperfec’ta Osteogenesis imperfecta (OI) is a genetic disorder that causes the bone to be fragile and break easily. It is also known as “brittle bone disease”. It is caused when there is a lack of collagen production. Collagen are what makes the bone strong, and the lack of collagen causes the bones to be weak and fragile, making it easier for it to break. OI affects 1 in 20,000 people. In the United States alone it is estimated to affect 20,000 at a minimum rate and 50,000 at the…
A fracture is considered compound when the skin is broken and the bone protrudes from the open fracture/wound. There is sometimes considerable soft tissue damage and a higher risk of infection from the open fracture. Immobilizing the injured leg will help to prevent causing more damage to the soft tissue around the break. Immobilization may also keep from causing injury to the femoral artery which could be fatal. Keeping the femur as still as possible after the break may also help doctors…
Approximately 2% of Canadians sustain a bone fracture every year. The majority of these fractures heal well; however, about 5 to 10% of fractures develop delayed or incomplete healing requiring additional medical intervention. While we understand some of the mechanisms controlling bone healing, an improved and in-depth understanding of the precise molecular as well as cellular mechanisms involved in correct bone formation during fracture healing is of great importance. The processes that occur…
Imagine waking up, tripping over a rug, and immediately breaking a hip bone or shoulder without any hesitation. With the right amount of calcium in your diet, this can reform immensely for the state of one’s bone health. The root “osteo” actually means bone; moreover, Osteoporosis is a disease in which the bone is tremendously brittle, which can be preventable with the right precautions. Bones are the formation of the skeletal system in which helps with mobility and structure. Unfortunately,…
Osteogenesis Imperfecta is a genetic disorder that causes extremely brittle bones. This disease can cause bones to break, people can have hundreds of fractures throughout their lifetime due to Osteogenesis Imperfecta. Most of Osteogenesis Imperfecta cases are caused by a dominant genetic mutation which would be types 1-4. Types 5 -8 are inherited by a recessive mutation. Although in some rare occasions is could be a new genetic mutation. The term “Osteogenesis Imperfecta” was originated by W.…
I do believe that there are circumstances under which a person should take calcium supplements. Calcium is one of the most abundant minerals in the body, yet so many people still have trouble consuming enough calcium rich foods. Calcium is by far the most important mineral for our structure. One circumstance under which a person should take calcium supplements is if a doctor specifically prescribes a patient a calcium supplement due to having any kind of deficiency. Another circumstance is if…
slows or prevents the development of cancer… There is a chemical in green tea that starves cancer cells” (Funk, K.) this is also supported in the Journal Article “Tea consumption and risk of ovarian cancer” (Nagle, C., Olsen, K., Bain, C., Whiteman, D., Green, A., and Webb, P. 2010) in which their results stated the same claim, though it was no concrete evidence “Our meta-analysis provided some evidence that women who drink green tea have a lower risk of ovarian cance” (Nagle, C.) although…
1. What is FOP? Fibrodysplasia Ossificans Progressiva is a rare genetic disease in which a person’s bones will begin to form into the muscles, tendons, ligaments, joints and connective tissues. Overtime the development will restrict a person’s movement. It has been described as turning a person into stone because their body is essentially encased by a second skeleton. 2. What are the initial symptoms? Symptoms of Fibrodysplasia Ossificans Progressiva, include: an infant being born with short,…
dded (a sub-process called ossi fi cation or bone formation). Remodeling involves continuous removal of discrete packets of old bone, replacement of these packets with newly synthesized proteinaceous matrix, and subsequent mineralization of the matrix to form new bone (FernándezTresguerres-Hernández-Gil et al. 2006; Fraher 1993) . These processes also control the reshaping or replacement of bone during growth and following injuries like fractures but also microdamage (prevents accumulation…
Dental implants are the standard treatment for gaps between teeth. When a gap goes unfilled, the jawbone will begin to lose mass, causing the remaining teeth to shift and tilt. The gums start to disintegrate and the overall oral health of the person becomes very poor. Soon, gum disease and tooth decay begin to form. There are several treatments for gaps, but dental implants actually restore bone loss and look and function like natural teeth. Dental implants are a long-term solution to tooth…