Virulence factor

Once the organism attaches, it uses several other virulence factors to evade host immune system, such as a polysaccharide capsule, OmpU, and siderophores. The polysaccharide capsule allows the organism to evade opsonization and phagocytosis due to its slippery property as well as allows the organism to be resistant to bactericidal properties of serum and hide its immunogenic structures from the host nonspecific defenses [25]. An outer membrane protein, called OmpU, allows the organism to bind to host fibronectin, thus improving its chances of adhering to the host [26]. V. vulnificus further produces two siderophores, vulnibactin and deferoxamine, which allow the bacterium to sequester iron for survival through the use of heme receptors (HupA) [27]. Vulnibactin specifically uses HupA to steal iron from host transferrins and holotransferrins due to it having a higher affinity for iron, and deferoxamine promotes organism growth and iron uptake [28]. Variation between virulent and avirulent forms of V. vulnificus depends on the presence of these three virulence factors. Virulent forms are almost always encapsulated, serum resistant, and possessing the ability to acquire iron from iron-saturated transferrin, while avirulent variants lack these characteristics…

When Life Gives HOPE! Everyone who has their dream has found their hope from factors they felt. Junior, a boy in The Absolute True Diary of a Part-Time Indian had experienced several factor shaping worldviews, but in the end even though some of his Spokane Tribe resented him for leaving, and he lost some people he truly cared about, he was about to find hope through the love and struggles he had come upon. Family support, race, education and friendship can contribute whether or not people can…

On May 25, 2016, the Manager met with YCWA General Manager Curt Aikens to discuss finalizing the Power Enhancement Agreement. Consistent with the previous meeting with the YCWA POD Committee, the Agency does not wish to explore the splitting of Gross Revenue and is citing several factors as the cause. The first is the 1990 Agreement that created the groundwork for the 2016 Agreement. The second, and perhaps most critical to each of our interests, is the growing prospect of other entities…

This article used the appropriate statistical procedures for the study. Using descriptive statistics and Pearson’s correlation allows the researcher to reveal if any correlation coefficients among variables are found. Also, using the path analysis to find the relationships among the variables was a key factor. The sample was significant for the study and the path analysis model because it required a large number of cases and this study had 2,565 participants. The responses from the survey…

The term entrepreneurial opportunity would usually presume a profit-motivated event. The adjective entrepreneurial emphasises that the profits are chased through creating a new good and presenting it to the market (Whetten, 1989). Other scholars define the entrepreneurial opportunity as situation that provokes the discovery of new goods, services, production technologies and organizing methods that are able to obtain some economic value in the future (Shane and Venkataraman, 2000). The…

The same is true for those who reject the idea and argue that education is not the only factor that affect production and economic growth. Certainly one can argue for wither side of the debate. However, Schultz’s argument is supported by empirical studies that show there is a direct correlation between education, wages, and the quality of input and output in production, thus economic growth. For this reason, individual who choose not to invest in higher education or lack formal training are at a…

completely controllable and predictable. This approach has certain requirements that include development of formal plans, centralized leadership and precise intentions. The planned approach is characterized with a specific mission, shared organizational intentions and realization of these intentions. This approach neglects the consideration of external factors such as changes in government policy, customer preferences, and introduction of new technologies (Hamilton & Webster, 2015). Such type of…

Article 71: Wind Turbines have always been a threat to birds who get killed by the blades of these turbines and the writer tries to explain how appalling this situation is for the environment in this article. The writer highlights how the U.S. Fish and Wildlife is seeking a public comment on a permit proposed for Shiloh IV wind project that will allow a wind project to kill up to five golden eagles over a five-year period, despite their protected status. Another double standard the writer puts…

that could play an important role in an individual’s tendency towards their entrepreneurial actions. (Marius Kahlert, 2015) How the aspects of entrepreneurial personality reflect upon the motivation and mindset of an entrepreneur can be explained quite simply. The personality of an entrepreneur is going to be a deciding factor on the way they think and how easily they are motivated. For example Neuroticism, or the emotional well-being of an individual, if one person is very self-confident the…

Crystal Methodology Critique, Benefits and limitations Crystal methodology was first bound by Cockburn in 1998. In crystal, the projects are divided according to their size and the criticality of the system being produced (Ramsin & Paige, 2008). Member of the crystal family is marked with a color to show the weight of the methodology, that means the darker the color the heavier the methodology. Crystal recommends choosing the appropriate color of methodology for a project based on its size and…