Virilization

Non-classical congenital adrenal hyperplasia or NCAH is a disorder that affects both men and women from late childhood through the rest of their lives. Compared to its sister form, classical congenital adrenal hyperplasia, it is non-life threatening. The Mayo Clinic, a service that gives people medical information and helps set up doctor appointments, defines NCAH as “a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones.” These vital hormones include, but aren’t limited to, estrogen, testosterone, aldosterone, androgens and corticosteroids. Non-classical congenital adrenal hyperplasia is an uncommon disorder affecting only one percent of the population in a 1 to 1000 ratio, according to the National Library of Medicine. From experience, this disorder is rather frustrating, difficult to manage, and painful at times but NCAH is treatable. At the cellular level of this disorder, non-classical congenital adrenal hyperplasia is a 21-hydroxylase deficiency, a common autosomal recessive disorder due to mutations in the CYP21A2 gene, according to Dr. Selma Witchel, a pediatric endocrinologist at Children’s Hospital in Pittsburgh. This disorder is hereditary when both parents carry the recessive gene for it or when one has the disorder and the other has the recessive gene. Genes are located in DNA, which is found in the nucleus of cells. “The mutation associated with NCAH generally indicates a 50–80% loss of enzymatic…

Abstract Background: Understanding the variation in progression from normal to precocious puberty is a matter of concern. Beside idiopathic central precocious puberty, CAH is an important cause of gonadotropin independent precocious puberty that requires a comprehensive treatment regimen to achieve normal growth and pubertal development. Aim of the work: This study aimed to evaluate growth and pubertal changes in children with CAH. Also, to consider the idiopathic central precocious puberty.…

Anadrolone Review – Facts you need to Know! Anadrolone, in one of the best steroid commonly used steroid by bodybuilders for mass gaining. This steroid also gains so much popularity because of its excellent Anadrolone reviews. All the steroids are developed for both mass gaining and for cutting purpose, but they work well only for one purpose. In this case, this is beneficial for both purposes. Most of the people use this steroid for increasing stamina, power output, and enhanced strength and…

It will give various benefits when it is being searched to improve athletic performance. In its highest dosage, it will relieve pain and heal the muscle tissues. It is most preferred over an opiate which works to mask pain. Deca is frequently combined with other drugs like testosterone, anadrol and dianabol. It is dissimilar to other steroids in repairing liver function. However all drugs from aspirin to anabolic steroid will cause side effects. Its highest dose may cause virilization symptoms.…

If the dosage taken exceeds 400-600 mg a week, certain sensitive individuals may experience hypertension or increased blood pressure, bleeding especially in time of cuts, over production of oil from the sebaceous glands which leads to acne, an increase in libido but at the same time a fall on sperm count and more. High blood pressure may also lead to frequent headaches especially in the nape area. We shouldn’t also forget that prolonged use of this drug especially of male athletes may lead…

A dosage of 250-750mg per week is more than sufficient to achieve great results. Some take advantage of the very low price of Omnadren (Europe) and take excessively large amounts. Beyond 750mg or 1000mg weekly added side effects will no doubt be greatly outweighing growth, so there is usually little need for such excess. With this drug we really don't want to mistake water bloat for muscle growth. And while a number of adventurous women do experiment with testosterone products, Omnadren is…

menstrual irregularities associated with hirsutism as in case of PCOS, Hyperprolactinemia etc conditions. 4. Family history- It runs in certain family, specific ethnic groups and also has some genetic influence. 5. Drug history - various drugs like anabolic steroids, danazol, cyclosporine, phenytoin, triamterene-hydrochlorothiazide, minoxidil, hexacholorobenzene, penicillamine, psoralens, hydrocortisone, oral contraceptives of nonsteroidal progestogen type, gluco-corticosteroids and…

Intersex (also known as hermaphroditism or DSDs) is a group of conditions with disparity between the external genitals and the internal genitals. There are 4 distinguished categories of Intersex, however in some cases, the cause remains undetermined, even with modern diagnostic methods. 1. 46, XX intersex occurs when a person has woman chromosomes, ovaries, but external genitals appear male. This is usually the result of a female fetus exposition to excess male hormones before birth. The labia…

Adrenal incidentaloma (AI) refers to an otherwise unsuspected adrenal mass found in up to 5 % of patients undergoing radiological imaging. As high as one in five incidentalomas are functional; hypersecretion of cortisol causing Cushing’s or Subclinical Cushing’s Syndrome (SCS), catecholamines leading to pheochromocytoma, aldosterone resulting in primary aldosteronism (Conn’s syndrome), androgens leading to virilization of patients, and in very rare cases renin manifesting as secondary…

Some problematic side effects of winstrol is an increase in your LDL and decreasing your HDL. Another side effect is testosterone suppression resulting in a decrease of testosterone levels below an optimal range. Other effects include loss of hair, deepening of the voice in women and body hair growth (Steroid, N.A). Dianabol side effects include acne, accelerated hair loss, reduction of testosterone, HDL suppression and LDL increases, negative role in blood pressure, and liver toxicity (Steroid,…