involvement, sometimes hemorrhagic, and early involvement of white matter are typical. The…
monocytes get infected, they can transmigrate through the blood brain barrier to infect the brain. This could be plausible if the monocytes were inefficient in early clearance of the virus. Nipah virus can also infect neuronal cells but cannot spread viral infection (13). Pathogenicity: In humans, Nipah virus colonizes mainly in nasopharyngeal and tracheal secretions during its early stages of infections which in later stages…
Yellow fever was an epidemic in the U.S. during the 19th century with cases reported as far north as Philadelphia. The last known case happened in New Orleans in 1905 resulting to many deaths. Flavivirus also know as Yellow fever virus is a RNA virus. The enveloped is spherical and about 50 nm in diameter. The surface proteins are composed in an icosahedral-like symmetry (Dao, 2010). Full grown virions contain two virus-encoded membrane proteins (M and E), while immature virions have a membrane…
been recognized and effectively dealt with in the past, but the present outbreak is becoming a overwhelming challenge. Approximately there have been 15,000 suspected cases of the disease and 6,000 confirmed deaths so far. The horrifying visual hemorrhagic symptoms caused by the Ebola virus include internal and external bleeding as well as the fear inducing statistics that the virus has a 90% mortality rate have both contributed to virus’s swift, overnight infamy. As a result of its mortality…
INTRODUCTION Public health is the establishment and maintenance of healthful living conditions for the general population. This goal requires organized effort from all levels of government, health institutions and individuals. There are three principle aims that underlie public health efforts. First is the assessment and monitoring of populations, from the community level to the national level, to…
huge frenzy in 1949 with symptoms like a fever and skin rash but a vaccination…
wrong and inhumane. However there is still a question as to whether or not research into biodefense, or the mechanisms used to battle bioterrorism (“Biodefense”), should be allowed. II. Background As previously stated, bioterrorism is the use of viral and bacterial diseases to infect populations and incite panic. These diseases can be found naturally, but can also be modified to be more contagious and resistant to medicine. The Centers for Disease Control and Prevention (CDC) classify…
(continuous–continuous) 3. Is there an association between patient gender and outcome among Ebola positive patients? (categorical-categorical) Ebola virus first encountered by the scientist in 1967.In the 1970s, first major outbreaks of hemorrhagic fever caused by Ebola virus occurred in the Democratic Republic of the Congo and Sudan.1 International scientific teams could not…
arenavirus Pichinde which does not bind to the α-DG receptor as control (2007). Fig 1.0(A) shows the percentage of infected cells for each of the multiplicity of infections (MOIs) through immunofluorescence staining for the conserved epitope of the viral GP. Fig 1.0(B) shows that a Laminin Overlay Assay (LOA) detected that the quantity of the glycosylated α-DG decreases as the MOI for LCMV increases while the western blot shows that cytosolic β-DG remains constant. In addition there is no change…
first known outbreak in 1976 is still unknown, but it is believed to have been caused by the human handling of fruit bats and monkeys. Once the virus snakes its way through the host’s body it causes deadly fevers which eventually produce hemorrhaging throughout the body of the victim. The hemorrhagic virus consists of seven proteins that make up the RNA’s genome by taking over the hosts’ cells to prevent the immune system from defeating the virus. Ultimately, the failure of internal organs due…