Parkinson’s disease is a neurodegenerative disorder, and as the name suggests it’s the deterioration of the brain over time, meaning as time passes by the disease will get worse. Parkinson’s disease causes malfunctions within the brain and its nerve cells called neurons. The brain is the control center of the human body and it is responsible for movement, coordination, regulation of organ function, our five senses, and the ability to produce and regulate hormones. The brain is accountable for…
Friedreich’s Ataxia (FRDA) is a progressive, degenerative multisystem disease. This is the most common autosomally inherited ataxia with an early age of onset and heterogeneous clinical phenotypes. FRDA patients predominantly show gradual deterioration of nervous system followed by cardiomyopathy and diabetes (Parkinson et al. 2013). The prevalence estimates vary greatly between 1 in 20 000 to 1 in 330 000 depending on the geographic region (Vankan 2013). The majority of the patients (98%) have…
Alpha-Synuclein plays a big role with getting Parkinson’s disease. Alpha -Synuclein has a symbol of SNCA gene, which provides instructions to make the small protein. The SNCA gene belongs to a family of genes called PARK (Parkinson disease) (Does the SNCA gene share characteristics with other genes ?). A gene is a unit of heredity that is transferred from a parent to offspring and is held to determine some characteristic of the offspring. The Parkinson disease is caused by mutations in the…
Parkinson's disease Definition: Parkinson’s disease is a progressive disease of the nervous system marked by tremor, muscular rigidity, and slow, imprecise movement, chiefly affecting middle-aged and elderly people. It is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine. Causes: Nerve cells use a brain chemical called dopamine to help control muscle movement. With Parkinson’s disease, the brain cells located in the substantia…
Parkinson’s disease is the most common type of Parkinsonism. It is also known as idiopathic Parkinsonism. The term idiopathic means “the cause is unknown” (Duvoisin, 1984). It is more common in older adults with the average age of onset being 60 to 61 years (Duvoisin, 1984). This disease affects about 1% of the population over the age of 60 and is more common in men than women (Gulli & Davidson, 2011). The cause of Parkinson’s disease is tissue death in the movement centers of the brain that…
Parkinson’s Disease: It is a genetic disorder that affects the central nervous system.This diseases’ common symptom is stiffness in the the body. People may experience trouble walking and moving. It often starts with tremors. It can also affect the voice and the eyesight. The self care way to help with this disease is to exercise and loosen up the body. Some medications include anti-tremor and a dopamine promoter. The anti-tremor works to stop and prevent tremors. Dopamine promoter is a…
Parkinson disease is commonly described as a progressive, neurodegenerative disease. It was first described in detail by James Parkinson in 1817. In his writing, “The Essay on the Shaking Palsy” he discusses signs of the disease that are still categorically descriptive of it today. Though not the first observation of the shaking palsy, his essay brought a lot of insight to the medical and scientific communities about this terrible, debilitating and incurable disease. Parkinson disease has…
AIM: Sarcopenia has been defined as an involuntary loss of skeletal muscle mass and strength and/or function. The presence of sarcopenia in patients with Parkinson’s disease (PD) may have prognostic effects and may be mistaken for poor therapeutic control of PD. We aimed to evaluate sarcopenia in patients with PD. METHODS: One hundred non-demented PD patients, and 95 healthy subjects were included in the study. Avarage-Muscle mass, weight, bone mass, fat mass, basal metabolism rate (BMR), body…
head. This could cause internal bleeding in the brain which would lead to the development of Vascular dementia. As seen to the right in figure 1, which depicts a normal brain and then a brain with Vascular disease. There is a clear difference between them because the one with Vascular disease (bottom) has holes in it. The holes in the brain are what cause memory loss. People who suffer from this condition often are bad at decision making, planning, and organizing things in their lives (“Types of…
neurocognitive diseases that compromise function of the frontal brain networks resulting in cognitive and behavioral deficits. FTNCD is a common cause of dementia among patients’ ages 45 – 65 years. This group of neurodegenerative conditions is characterized by progressive and relatively selective atrophy of frontal lobes, temporal lobes, or both, and deterioration in behavior and personality or in language abilities culminating in dementia (DynaMed, 2016). Vascular neurocognitive disease (VND)…