U.S. Route 3

:-के.वि.वीरभद्रप्पा 2. TITLE OF THE RESEARCH :- Pharmacognostical, Phytochemical and Pharmacological activity of Sesbaniagrandiflora (L.) PERS Hindi : फार्मकोज्ञोस्टिकल, फयटोचेमिकल आंड फार्मकोलॉजिकल आक्टिविटी ऑफ ससबानियाग्राणदिफलोरा (एल.) पर्स 3. LOCATION 1. Organization/Department where the work is to be done : Deapertment of Pharmacognosy, Raghavendra institute of pharmaceutical education and…

CHAPTER-V FORMULATION AND EVALUATION OF LEVODOPA FLOATING TABLETS FORMULATION AND EVALUATION OF LEVODOPA FLOATING TABLETS Several approaches are currently used to retain the dosage form in the stomach. The principle of the floating tablets is simple and practically approach to achieve increased gastric residence time to obtain controlled release floating tablets designed based on the gas generating principle needs a strong floating matrix former. In this regard HPMC K4M,…

During formulation development, 3 different disintegrating agent s, were utilized to prepare immediate release tablet which are Sodium starch glycolate, Crospovidone and Cross carmellose sodium. Tablets were evaluated for disintegration time. Sodium starch glycolate, Crospovidone and…

Following intravenous administration, there is no absorption process since the drug is directly introduced into the blood stream. However, for oral routes, there will be an absorption process that occurs. Following ingestion of a drug it begins to dissolve in the GI fluids and is absorbed into the blood. While the transportation of the drug in the gut wall, if any process becomes saturated, then increases…

dermatoses complicated and/or bacterial infections, such as: 1-Atopic dermatitis 2-Seborrhoeic dermatitis 3-Lichen simplex chronicus 4-Psoriasis (particularly of the face and body folds) Allergic contact dermatitis.  Contraindications: 1-Sensitivity to any of the components of the preparation. 2- Not indicated in those patients with tuberculous lesions, topical or systemic viral infection. 3-KENACOMB is not intended for ophthalmic use, nor should it be applied in the external…

The benefit of using micelles as DDS is to increase the blood circulation time, which in the cases of NK91125 and SP1049C26 were by a factor of 3 in comparison to the free drug. Issues surrounding the utilization of more micelle formulations include insufficient drug loading, stability, and selective uptake by targeted cells17. A common misconception is that micelles are not solid structures or…

ABSTRACT Solubility is the phenomenon of dissolution of solid in liquid phase to give a homogenous system.Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation for pharmacological response to be shown. Poor watersolubledrugs often require high doses in order to reach therapeutic plasma concentrations after oral administration. Low aqueoussolubility is the major problem encountered with formulation development of new chemical entities. Any…

Microneedles Insulin is most effectively taken through direct injection, which is most typically done through a needle. Traditional needles are bulky and are oftentimes associated with pain. Microneedles are much smaller in dimensions, making them able to effectively release insulin into the body while not reaching nerve cells which would cause pain and discomfort. Microneedles are designed to puncture only the top 20–50 μm of the skin, because the stratum corneum, which is the outer layer…

low first pass digestion system 3. cause GI disturbance Lornoxicam is the medication has a place with the BCS class II which have high penetrability so the ethosomal gel readiness of the medication competitor is suitable. The medication is utilized for pain relieving, mitigating so…

The aim of the present investigation is to intend, develop and evaluate a pulsatile drug delivery containing a core-in-cup based system of dry coated tablet of ketoprofen based on chronomodulated approach for management of Rheumatoid Arthritis. This pulsatile system contained a core tablet surrounded by an impermeable outer shell and top cover layer. Core tablet contained the active ingredient acting as reservoir, ethylcellulose was used to form an impermeable outer shell, the top cover layer…