Tuberous sclerosis

Phantom limb pain is defined as “pain perceived by the region of the body no longer present” (Subedi & Grossberg, 2011, p.1). This type of pain can be described as “shooting, severe burning, ischemic or crushing in nature or severe from…the limb being in a hyper-extended or unnatural position.” (Chapman, 2010, p. 35). Phantom limb sensation is the “nonpainful sensations experienced in the body part that no longer exist…phantom sensations are touch and pressure-like sensations.” (Subedi &…

Guillain-Barré Syndrome Guillain-Barré syndrome (GBS) is not something that many people have dealt with or even heard of for that matter. According to the CDC, there is somewhere between 3,000-6,000 cases of GBS per year in the United States. That amounts to 1-2 people out of 100,000 per year (CDC, 2009). For me, Guillain-Barré syndrome is something that I have known about since I was eight years old. Not only was I aware that it existed, I thought it was going to take my dad away from me.…

Multiple Sclerosis is a chronic, progressive, degenerative disorder of the central nervous system. This disorder usually affects young adults between the ages of 20 and 40. Multiple frequency of occurrence is rare, .1% currently afflicts about 400,000 in the United States and 1 million worldwide. The cause of multiple sclerosis is unknown, but it is likely that multiple factors act in concert to trigger or perpetuate the disease. It has been hypothesized that multiple sclerosis results when an…

Introduction Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, affecting nerve cells in the brain and the spinal cord. To better understand the breadth of this disease, it is vital to define the following terms. The word amyotrophic means “without muscle nourishment”, which refers to the loss of signals the neurons normally send to the muscles. Lateral means “to the side”, which refers to the location of the damage in the spinal cord. Sclerosis means “abnormal…

The first description of a Huntington-like disease dates back to the late 1800’s where George Huntington coined the name Huntington’s chorea. It is characterized as a neurodegenerative disorder passed within families within generations as an onset of unwanted choreatic movements, behavioral and psychiatric disturbances and dementia [1]. The name Huntington’s chorea eventually changed to the well-known Huntington’s Disease (HD) due to the recognition of other debilitative symptoms developed along…

Guillain-Barre Syndrome is a disorder that affects the peripheral nervous system. It is an autoimmune disease that forms antibodies against peripheral nerves. There is no definite etiology for GBS. This disease shows different symptoms depending on the type of GBS and its severity. Treatments are available for people who have this disease, but as of now, there is no cure (Biomarkers). An exact cause of GBS has not been found, but its symptoms have been noted to follow a pattern. In most cases,…

Chronic Inflammatory Demyelinating Polyneuropathy Chronic inflammatory demyelinating polyneuropathy (CIDP) is a condition in which your nerves do not work as they should. When you have this condition: You may feel less sensation than before. You may have unusual sensations. Your muscles may not work normally. CIDP occur along with a blood disorder or another condition, such as diabetes, HIV, hepatitis B or C infection, Waldenstrom’s macroglobulinemia, multiple myeloma, and…

This disease is a result of of damage to your nerves which causes pain, numbness and weakness of hands feet, etc. these nerves send signals to your brain and information. Every nerve in your peripheral system has a specific function, so symptoms depend on the type of nerves affected. Signs/ factors: • Gradual onset of numbness and tingling in your hands and feet, which may spread upwards into your legs and arms • Sharp jabbing • Extreme sensitivity to touch • Lack of coordination and falling •…

Multiple Sclerosis and the EAE model Background: Multiple sclerosis is a chronic inflammatory disease that affects the CNS (brain and spinal cord). MS attacks the myelinated axons in the CNS, causing adverse effects in motor and autonomic function. The four major categories of MS are relapsing-remitting MS, secondary progressive MS, primary progressive MS, and progressive-relapsing MS but the course of the disease remains very unpredictable. Although tests to diagnose MS do not exist, studies…

Multiple sclerosis is a standout amongst the most misjudged illnesses of this century. Since its disclosure, there are still no known reasons, no demonstrated medicines, and no known cure, yet it influences conceivably five hundred thousand individuals in the United States alone. Individuals need to take in more about this infection so it can be conveyed to the country's consideration. Different Sclerosis is a focal's ailment sensory system. It pulverizes the greasy myelin sheath that protects…