assay (ELISA). The toxicity of menadione (VK3) and the protective effect of Borsub against VK3 were studied in ARPE-19 cells with cell survival assay. Autophagy activation in ARPE-19 cells by Borsub was examined with western blotting and immunofluorescent confocal laser microscopy.…
The popularity of energy drinks among teenagers and young adults has been increasing in the past decade with the emergence of the energy drink “Red Bull” back in the late nineties. There are now over 300 variants of energy drinks offered in the US and some of them are available everywhere: corner store, grocery store, restaurants, bars and even vending machines. The top four energy drinks company, Red Bull, Monster, Rockstar and NOS are often misleadingly advertised in sports, popular youth…
This toxicity will have come from many possible sources and include heavy metal toxicity, traffic fumes, food flavourings and colourings and preservatives, prescribed or OTC medications (which may or may not have been taken for ADHD), pesticides to name but a few. Of course we are all exposed to…
Because every living organism on the planet is part of the ecosystem I thought it was important to incorporate what Chemtrails do to the human body. The deterioration of cognitive function is just one effect of Chemtrails on our immune system. The skin, being the largest organ in our body, is a permeable membrane. This means that invisible toxins in our air, including Chemtrails and other highly dangerous chemicals, go right into our skin. Poisoned rainwater or snow touching our skin does the…
vasopressor to increase the heart rate and vessel tone by activating the sympathetic receptors found within the heart and vessels. High dose insulin therapy may also be utilized intravenously if the patient is hyperglycemic from the calcium channel blocker toxicity. It is imperative to monitor the patient’s blood glucose and administer glucose when needed to prevent insulin-induced hypoglycemia. Glucagon can also be administered intravenously in patients with refractory hypotension. If all of…
Objective This experiment is designed to investigate the IC 50 of compounds which had the positive effect on the reduction of the viability of leukemia cells. Introduction IC 50 stands for “half maximum inhibitory concentration” (2). IC 50 represents the concentration of the compounds that required for 50% of cell death. The IC 50 assay is used to determine the potency of the drugs which used as treatment of cancers (1). In the previous experiments, 20,000 cells/mL was the optimal number of…
Specifications in Cosmetic Ingredients The toxicological specifications for cosmetic ingredients are (Pauwels & Rogiers, 2004): 1.Acute toxicity. 2.Irritation and corrosivity. 3.Skin sensitization. 4.Dermal/percutaneous absorption. 5.Repeated dose toxicity. 6.Mutagenicity/genotoxicity. 7.Carcinogenicity. 8.Reproductive toxicity. 9.Toxicokinetics. 10.Photo-induced toxicity. 11.Human data. These are all vital checkpoints for determining if a cosmetic product is suitable for sale and…
There is a growing body of evidence to support that intensive individualized nutritional counseling can be beneficial to cancer patients by helping them to increase their dietary intakes as well as forestall weight loss and treatment interruptions associated with therapy. In fact, the European Society for Clinical Nutrition and Metabolism guidelines have a recommendation that promotes the use of individualize counseling and the use of high-protein dietary supplements increase food intake in…
highly unsaturated fatty acid freshly obtained from cuttle fish oil showed quite the same good nutritive effect as oleic acid ester for rat, while the acid exposed to air was proved to be extremely toxic. Since it seems to be most plausible that the toxicity is concerned with the formation of peroxide by autoxidation of unsaturated fatty acid, the author determined the amount of peroxide. The result proved. this was just the case, the details of which will be reported here. EXPERIMENTAL The…
Question 1: As a senior healthcare administrator that is part of the Central Indiana Ebola Preparedness Team I have reviewed many policies and procedures to develop an ethical plan for the management of Ebola in Central Indiana. The main objective of this plan is to be as prepared as possible and follow all protocols or clinical practice guidelines that are put into place. We must coordinate with healthcare facilities locally and statewide to put the plan into place. The first step is to have…