In conclusion, we reported the synthesis of fused and isolated triazoles based on thieno[2,3-d]pyrimidines. The synthesized 1,2,4-triazolo compounds were screened for their anticancer activity at a concentration of 10 μΜ against a panel of 60 cell lines derived from nine different types of cancers, and also screened for their PDE 5 inhibitory activity. The possibility of combining 1,2,4-triazolo moiety to thieno[2,3-d]pyrimidines should open new opportunities for the rational design of…
In many people’s minds, the term “Fracking” only applies to the controversial extraction process and the environmental impact surrounding that process. Hydraulic Fracturing or “Fracking” for short is a process where chemicals and water are injected into wells to breakup rock formations that have gas or oil trapped in the rock itself. This process is specifically used for developing and extracting oil and natural gas from shale. While most people have heard the term “Fracking”, very few…
as methane, volatile organic compounds (VOC’s), sulfur dioxide, aromatic hydrocarbons, and benzopyrene. Methane, VOC’s, and sulfur dioxide are known to exacerbate asthma and worsen other respiratory problems. Aromatic hydrocarbons such as benzene, toluene, and xylene are known carcinogens. Furthermore, if the flare stacks do operate by design, they can still cause harm to wildlife by the means of attraction. The flame from the flare stacks attracts insects and birds. “Approximately 7,500…
In this essay, I will be highlighting the negative effects of hydraulic fracking in its role of causing potential damage to the environment and contamination of groundwater. Hydraulic fracking is defined as the injection of liquid fluid at high pressure that extracts oil or gas. In Cart’s article, she denotes how this issue is very problematic because both oppositions have different opinions. For instance, the companies she interviewed disregard the potential damages from fracking and state…
that is found in your common household cleaners and Benzene that is found in rubber cement. On top of those four you can also find Arsenic, Butane, Cadmium, Carbon Monoxide, Formaldehyde, Hexamine, Lead, Naphthalene, Methanol, Nicotine, Tar, and Toluene. All of these chemicals come from products that should not be put inside the human body. While there is still a lot of unknowns about e-cigarettes there are a few things that a for sure known to be inside of them. “Since 2009, FDA has pointed out…
Raju Chandra et al; A reliable and reproducible reversed-phase high performance liquid chromatography (RP-HPLC) was developed for the quantitative determination of quetiapine fumarate from marketed bulk tablets. The active ingredient of quetiapine fumarate separation achieved with C18 column using the methanol water mobile phase in the ratio of 30:70 (v/v). The active ingredient of the drug content quantify with UV detector at 359 nm. The retention time of quetiapine fumarate is 5.27 min. A good…
This chapter discusses about the health hazard and hygiene in the workplace. Hazards can be found in every workplace. Hazard is generally anything that makes you in a dangerous situation. Health hazard is means that the hazard brings negative effect and harm to the health which is may cause measurable changes in the body. There are many hazard in the workplaces have the potential to harm workers short-term and long-term health result in diseases, disorders and injuries (Alison et. al., 2008).…
INTRODUCTION For years, smokers and non-smokers have yearned for a new and less harmful alternative to conventional cigarettes. Both factions know the health implications of inhaling traditional cigarette smoke, both directly and indirectly (second hand smoke), and have pressed for alternatives, thus creating the market for electronic cigarettes. The advent of the electronic cigarette (e-cigarette) was in the year 2007. The revolutionary product is quite similar to conventional cigarettes…
Goals The overall goal of this project was to identify an unknown ionic compound; each group was assigned a small container filled with 5 grams of an unknown ionic compound. In order to be able to identify the unknown compound, we had to do several preliminary tests, cation tests, anion tests, and a reactivity test. Throughout these three weeks, we will identify a compound and its qualities just by looking at it. We also made quantitative and qualitative solutions and tested the compounds' pH,…
Fracking, also known as hydraulic fracturing, is a type of drilling that uses water, sand and chemicals, shot at high pressure, to release energy resources trapped inside rocks. This recently new technology for drilling allows areas that were previously inaccessible for drilling, like very concentrated rocky areas, to now be opened up through fracking to obtain natural gases and oil. The water solution used with this drilling technique produces almost the same amount of “sludge” as an after…