TLC

chromatography (TLC) to identify the active analgesic ingredient of Advil and monitor the transesterification of methyl salicylate from acetylsalicylic acid. The synthesized methyl salicylate was then purified using acid-base chemistry and analyzed using H NMR spectroscopy. Identification of a proper mobile phase to separate common analgesics used in over-the-counter pain relievers was essential in being able to determine the active ingredient in Advil. Therefore, in Procedure 1 TLC trials…

The transition from freshman year to sophomore year is an experience I will never forget. It is no secret that change can be difficult, but no one could ever adequately prepared me for this great transition. Despite an infinite amount of advice, experience is the best teacher; unfortunately, experience is tough to set up a meeting with and sadly doesn’t have office hours. This is one of the main reasons why I want to be a second-year peer mentor. I want to make that transition from freshman year…

equal to the actual yield over the theoretical yield times 100. Since the theoretical yield was 0.00056M, the result was a 34% yield. The melting point was found to be 262.7 oC, which lies within the correct range theoretically. The results of the TLC plate testing also concluded that the product was pure. The spot from the product appeared half way up the card while the anthracene was at the top and the maleic anhydride was at the bottom. This single dot indicates a pure…

alcohol or chemicals in blood and also for crime scene investigations (forensic evidence). Used in the separation of amino acids, carbohydrates, fats, vitamins, and more: Done for extensive research and even medical purposes. Thin Layer Chromatography (TLC) Thin Layer Chromatography is a chromatographic technique used to separate the components of a mixture using a thin stationary phase substance. It is operated similarly to paper chromatography. Materials Silica Plate, Tweezers & Gloves,…

Caffeine is found in many products such as in pharmaceutical supplements, and beverages. Caffeine is mainly obtained from plant seeds or tea leaves. Extraction of caffeine is done to make decaffeinated coffee. There are three methods used to extract caffeine such as water extraction, supercritical carbon dioxide extraction and extraction by organic solvents. For this lab, the method used to extract caffeine will be by organic solvents. The purpose of the procedure is see how caffeine is isolated…

too deep, the spots on the TLC plates will become submerged and alter the results, too shallow and the solvent will not be able to make it to the desired height on the plate. Since these solvents are generally volatile, a piece of filter paper was added to the jar that had been soaked in the solvent in order to saturate the air inside the sealed jar to prevent evaporation from the plate. The jar was left sealed for about five minutes to ensure air saturation while the TLC plates were prepared…

A important tests were performed on the product to pressure the results: melting point value, percent yield, IR, and TLC. The experimental melting point value was found to be a range of 165-167 ºC being a little lower than the literature value for camphor, the intended product, was 175 ºC. The sharp range was resulted in a slightly pure product. The percent yield was lower than expected which can be the reason most of the product was lost during the extraction and almost completely sublimated…

The solvent systems separated fluorene and 9-fluorenone based on their difference in structure and polarity. The petroleum ether solvent system was helpful in washing away anything that was hydrophobic since it’s nonpolar, and it essentially washed off most of the fluorene since fluorene is not as polar as 9-fluorenone. The solvent system with a mixture between Dichloromethane and petroleum ether allowed the yellow band to be eluted off the column because polar solvents such as Dichloromethane…

Dr. Damaris Garcia was born and raised in ______________________________. She moved to the United States where she studied at the University of ______________, . While attending college she worked as a veterinary assistant at ______________________. Dr. Garcia received her doctorate from the University of____________ in 20___. Growing up she had an extensive love for animals, and has always been a pet owner. Currently, she is the proud owner of a _________ named ________ and a_______…

compounds. The compounds that matched the sample were then tested through a mixed melting point that ensured proper identification and whether impurities were present in the isolated compounds. The compounds were found to be benzoic acid and benzoin. TLC was then conducted to determine if impurities were present. The IR spec was then conducted to ensure proper…