Thrombosis

According to NICE (2010) “A UK survey suggested that 71% of patients assessed to be at medium or high risk of developing deep vein thrombosis did not receive any form of mechanical or pharmacological VTE prophylaxis”. The guideline emphasized the need for mechanical or chemical prophylaxis especially for post-surgical patients because these are the patients who have significant reduced…

It is my great pleasure to write this supporting letter for Dr. Tomokazu Amano’s application for an assistant professor position. Currently, I am the Principle Investigator (Title: Senior Research Fellow) in the MRC Centre for Reproductive Health, University of Edinburgh, UK. The interests of my laboratory are to understand the epigenetic reprogramming that occurs during the oocyte-to-zygote transition, pre-implantation stages and the establishment of totipotency/pluripotency. I have known…

Thank you for contacting us. We're currently working with Dr. Stacy Johnson to automate the process of identifying PE and DVT patient cohort. For the PE task, we want to determine whether a patient has PE or not, if so, whether the PE is acute or chronic and its artery level. For the DVT task, we want to determine whether a patient has VT or not, superficial or deep, proximal or distal, acute or chronic, left or right, upper limbs or lower limbs. For both tasks, we also want to determine if the…

This essay will be based on a case study that focuses on a registered nurse and the care that was given to one of her patients which will include patterns of knowing and bioethical principles, which should have informed the nurse about the possible actions she could have chosen for a possibly better outcome for the patient. Four elements of negligence that must be met in order for the nurse to be considered legally negligent. Along with the (NMBA) nursing and midwifery board of Australia 's…

rare thrombophilic and hematopoietic stem cell disorder with an annual incidence rate of as low as 1-2 cases per million. About 16% of these patients present with visceral vein thrombosis which is the most common cause of mortality. We here present an extremely rare case of a young man presenting with extensive thrombosis of multiple visceral veins from PNH. A 36-year-old Hispanic man with no significant medical history presented to the emergency department with diffuse abdominal pain of 4 days…

Venous thromboembolism (VTE) is a single disease affecting the venous circulation. It has two distinct presentations of condition that are the deep vein thrombosis (DVT) and the pulmonary embolism (PE) [1]. The DVT condition commonly occurs in the deep vein of the lower limb or pelvis. Figure 1.1 shows the structure of vein at the lower limb. Furthermore, it can also develop anywhere in the body, such as the veins in the arm, abdomen, or around the brain.A blood clot that forms in the arteries…

CORONARY STENTS Before stents were used, balloon angioplasty was used to treat narrowed coronary arteries. This involved inserting a very thin, long, balloon-tipped tube into an artery where there was a blockage. The balloon at the tip of the catheter was inflated to compress the blockage and restore blood flow. It was then deflated to remove the catheter and balloon but because no support was left at the site of the blockage, in some cases, the artery collapsed. This is why small stents were…

(PAI-1) PAI-1 is used to evaluate the risk of thrombosis. It is a serine protease inhibitor (serpin), therefore it is also known as serpin E1. Human SERPINE1 gene encodes for PAI-1. PAI-1 inhibits Fibrinolysis through the inhibition of the serine proteases, Tissue plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), which activate plasminogen. So any increase in PAI-1 decreases fibrinolysis consequently increasing the risk of thrombosis. PAI-1 gene (SERPINE1 gene) is…

Question 1 What are her risk factors for developing a VTE? (Identify all factors) Answer to Question 1 The risk factors that predisposes Mrs. X to develop a venous thromboembolism (VTE) are: advanced age, malignancy (cholangiocarcinoma), trauma (multiple falls), and recent major livery surgery (Schwartz & Rote, 2014, p. 1048-1050). Patients who are in their advanced ages are at risk in developing a VTE due to slower blood flow in their veins (Schwartz & Rote, 2014, p. 1048). Additionally,…

clinical at KU Rehab Center were postoperative deep vein thrombosis and decubitus ulcers. Spath (2011) reminds readers that patient safety indicators are events that are potentially preventable. As nurses it is our job to do everything we can to keep these issues to a minimum during every patients stay. During my time at clinical I watched nurses complete multiple pre-emptive measures to keep their patients from getting ulcers and deep vein thrombosis. Decubitus ulcers were very rare at KU…