Thrombocytopenia

Breast cancer in females TERMINOLOGY CLINICAL CLARIFICATION ? Malignancy that develops in the cells of the breast which proliferates uncontrollably; most commonly ductal and lobular carcinoma ? Diagnosis requires a tissue biopsy for microscopic examination to determine pathology CLASSIFICATION ? The TNM classification is used for clinical staging of breast tumors. The American Joint Committee on Cancer (AJCC) 7th edition stages breast cancer as follows:?26 ? TX: primary tumor cannot be…

INTRODUCTION Oral Controlled Release Drug Delivery Systems1, 2: Oral controlled release drug delivery is a drug delivery system that provides*give the continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specific region within the GI tract for either local or systemic action. All the pharmaceutical products formulated for systemic delivery via*throw…

QUESTIONS 1. Discuss the pathophysiology of coronary artery atherosclerosis. Include discussion of risk factors associated with the development of this disease. (10 points) Coronary artery atherosclerosis is most commonly comprised of atherosclerotic fibrous fatty obstructions of the large epicardial vessels, which provide for blood flow and transport nutrients, oxygen, and elimination of metabolic waste products such as CO2, lactic acid, and hydrogen ions. Coronary artery atherosclerosis…

all types of cancer. These include weight loss, poor appetite, fatigue and wasting (known as cancer cachexia), excessive sweating especially at nights (night sweats), hormonal changes, anemia, bleeding tendencies due to deficiency of platelets (thrombocytopenia) etc. Symptoms of spread of cancer or metastasis This includes swelling of the nearing lymph…

According to Schouten et al (2008), sepsis involves the activation of the coagulation cascade coupled with down-regulation of anticoagulation and fibrinolysis. An intricate link between inflammation and coagulation exists within the body (Neligan, 2006). When a pathogen is present in the bloodstream or when tissue injury occurs, an inflammatory response occurs. The response causes a stimulation of the immune system to produce interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis…