Thrombocytopenia

associated with considerable morbidity and mortality, particularly in elderly patients and those with significant comorbidities (Thomas et al., 2013). In addition to being part of the hemostatic process, platelets have been increasingly recognized as an important component of the immune response to infection (Katz et al., 2011). Platelets are important inflammatory cells that can undergo chemotaxis and are able to release numerous proinflammatory molecules (Elzey et al., 2005). Thrombocytopenia is a recognized marker of poor outcome in patients with pneumonia, due to the association of low platelet counts with severe intravascular coagulation and severe sepsis. (Mandell et al., 2007). Conversely, thrombocytosis has often been considered a sign of normal inflammatory reaction, but not as a marker of poor outcome. The clinical profile, inflammatory biomarkers, and mortality in patients with CAP may be different in those presenting with thrombocytosis and thrombocytopenia than in patients with normal platelet…

that help in the detection of lupus are fortunately available. These tests include echocardiograms, antinuclear antibody test, urinalysis, erythrocyte sedimentation rate, and complete blood count (Mayo clinic Staff, 2014). Treatment of the disease is highly dependent of the symptoms the person has. Since the disease is autoimmune, it is hard to treat and is therefore treated by managing the symptoms with drugs such as immunosuppressants, NSAIDS, corticosteroids and antimalarial drugs. Early…

inflammatory and cardiovascular diseases will develop (Machin & Briggs 2010). The findings of the main study evidently exhibited MVP to be most stable while in citrate. Such was because of the significant change of MPV while in EDTA. Whereas, platelet counts were found to be most stable while in EDTA. According to the study results, a close correlation emerges between MPV measurement provided by EDTA and citrate. With MPV measured by EDTA exceeding the case of citrate, this confirms the previous…

Recommended Testing Lactate Level Blood Cultures X 2 (Different Sites) - Prior to initiating antibiotics Culture Surgical Site and Gram Stain Complete Blood Count with Differential (CBC) Complete Metabolic Profile (CMP) Blood Glucose Monitoring Prothrombin Time (PT) and International Nectrotizing Ratio (INR) Activated Partial Thromboplastin Time (aPTT) Urinalysis (UA) and Culture CT Abdomen/Pelvis Radiograph of Right Lower Extremity The given scenario leads this writer to pursue aggressive…

Final Paper: Measuring Change in HRQoL of ITP Patients in Japan treated by Eltrombopag Introduction Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder, which is characterized by a low platelet count caused by both increased platelet destruction and insufficient platelet production [1]. In Japan, there are 20,000 patients with ITP and the incidence of ITP is estimated at 3,000 per year [2]. Major signs and symptoms include red spots and/or bruising on the skin, prolonged…

Why is math important? Some people cringe when math is mentioned, but whether they favor it or not, numbers can’t be avoided. Math is present everywhere whether it be cooking, shopping, creating, caring for others or etc. According to the history, counting supposedly started right after the development of language. Egyptians had used Egyptian system around 3000-1600 BC which they wrote 10 as ^ and 13 as III^. This system was adapted by the Romans in their roman numerals. Egyptians also has the…

Signs and Symptoms There are a few indications to look out for when thrombocytopenia is the suspected disorder an individual is suffering from. We know that thrombocytopenia is caused by a low platelet (Thrombocyte) count which would result in a bodies hindered ability to perform important blood clotting functions [2]. Most of the time the symptoms aren’t life threatening and in mild cases the person suffering from the disorder doesn't even experience any related symptoms [3]. In severe cases,…

Immune thrombocytopenia purpura (ITP), is a blood disorder that is characterized by the destruction of the blood platelets caused by the presence of antiplatelet antibodies. This bleeding disorder is not associated with a systemic disease. It’s typically chronic in adults, but self-limited in children. The trouble with this there is not defining diagnostic that presents this disease clearly, instead the diagnosis is presented through the exclusion of other variables. Typically, patients have…

syndrome ( WAS) patient presented with unusual laboratory features . Clinical Presentation and Intervention. Male neonate admitted with symptoms related to thrombocytopenia,whose initial diagnosis were considered as neonatal alloimmune thrombocytopenia and JMML (Juvenile myelomonocytic leukemia) but subsequently diagnosis confirmed as WAS. Conclusion. This case shows that a suspicion of WAS is warranted in the setting neonatal thrombocytopenia with JMML like blood picture & normal sized…

Low Platelets During Pregnancy Having low blood platelets during pregnancy is the second most common type of blood disorder after anaemia. Between 5-8% of women will be diagnosed with a low blood platelet count, or thrombocytopenia, during pregnancy. Very rarely can this be a problem during pregnancy or birth but it is a good idea to be prepared for the potential impact if you are told your platelet levels are low. What Are Platelets? Platelets are plate shaped cells that circulate in…