The Cancer Genome Atlas

perseverance award with a standing ovation from the audience on TV, I lost it. That moment was the last straw. Savannah Hart is loved by the entire world. Little kids all across the nation look up to her. She singlehandedly discovered the cure for cancer while devoting her life to helping the school districts of New York City and the education system in Africa. Nevertheless, she does all this while coping with a serious heart condition. "How does she do it?” is a question that gets asked by people across the world everyday. I am going to let you in on a little secret: She doesn’t. Savannah Hart is a fraud. Here’s how “She did it." Back in Yale, The Remedium Institute, a secret research center known by few for its groundbreaking discoveries in research, were looking to hire a fresh, college student. It was me vs her. We were both trying to land the job, but we knew only one of us would get hired. After weeks of being evaluated and interviewed, I won the job. My career was taking off as I was the youngest person to be hired by The Remedium Institute. For the first years of my career, I worked with a team of scientists on cancer research. We worked crazy hours. After countless nights of no-sleep, my team discovered a medicine that cured the cancer in rodents. We were days away from a cure in humans.…

make it efficiency. This could be an example for building awareness about ovarian cancer although this has not become the serious issue in the world, it need time and people’s attention to build this up. Instead of immediate information about missing children, an App could be a better way to express the ovarian cancer. The App should contain what is ovarian cancer and how serious it would be. ovarian cancer is dangerous to every signal and this would be specifically represent in the app and this…

Introduction The Human Genome Project was a research program that began in 1990 and took 13 years to complete (1). The project was originally funded by the US Department of Energy and the National Institutes of Health. Additionally, many other countries participated, including the UK, Canada, Japan, France, and Germany (1). The overall aim of the Human Genome Project was to completely understand and map out every human gene, the genome (2). The other goals of the program were to determine the…

The Cancer Stem Cell Hypothesis: A Basic and Clinical Approach to Treating Glioblastoma Multiforme Introduction Glioblastoma (World Health Organization grade IV glioma; GBM) is the most prevalent and malignant primary brain tumor in adults, and it is predominantly drug and radiation resistant1. Unlike many other solid tumor types, GBM extensively invades the surrounding brain, but it rarely metastasizes to other organs. Beyond its invasive nature, there are a variety of other hallmarks of…

Importance of studying cancer Cancer is a vastly complex disease exhibiting a plethora of genomic alterations and resulting regulatory failures at the root of its progression. Following the milestone of the Human Genome Project (HGP) era, researchers are now focusing on integrating the rich genome-wide association studies (GWAS), single-nucleotide polymorphism (SNP) data, and identified gene signatures within the in vitro, in vivo and clinical frameworks to further our understanding of the…

stem cell is the immature cell that is generated from an adult cell and regained the capacity to differentiate into any type of cell in the body. The genome is the total genetic information carried by an organism. The 10K Genomes Initiative was the plan to sequence all DNA from 10000 species. The Human Genome Project established databases and refined analytical software to make data available on the Internet. Bioinformatics and genomics are two terms that are often hashed up. While…

portion of the population, that each and every person is truly biologically unique, from our fingerprint to our genome (Topol, 2014, p. 241). This has now been made abundantly clear through the use of compressive ‘omic’ assessments of individuals, including DNA and RNA sequencing, and to a lesser extent the metabolone, proteome, and even the microbiome, autoantibodies and epigenome (Topol, 2014, p. 241). This information can now give rise to the exceptional and unparalleled opportunity to…

Cancer represents a heterogeneous group of diseases. It is characterized by uncontrolled cell growth and a collapse of all multicellular co-operations (Zhang, et al., 2016; Zhang and Sun, 2015; Zhong, et al., 2016). Cancer promotes tumor development and metastasis (Ahmed, et al., 2013; Zhu, et al., 2016). Tumors are characterized by six essential alterations in cell physiology. These are self-sufficiency in growth signals, continued angiogenesis, insensitivity to growth inhibition signals,…