Suppressor

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

The wide field of biochemistry includes exploration in the use of gene therapy for the treatment of cancers such as lung cancer. Though gene therapy is still in early stages of development, many researchers have concluded that gene therapy in therapeutic cancer treatment seems to be very effective and efficient. Gene therapy is the replacement of defective genes to enable the production of normally functioning genes. This replacement of genes is an adolescent and risky procedure and is often…

made out of aircraft grade7075-T6 aluminum making it lightweight and corrosion-resistant. The design allows the use of different accessories like a vertical forward grip, electronic sight systems, lighting systems, night vision devices, sound suppressors, etc. The AR-15 rifles modular design, which uses drop in parts, also makes repairing it easier…

and ambition entitle him.” Hoover’s conviction of government to provide American citizens an equal opportunity to succeed showed his disdain for regimented systems of class whether it be communism or a historically stratified class system, as suppressors of the power of the individual to drive progress. His individualism took the form of a “meritocracy with a heart…view[ed] the people not as masses or classes or races but as individual human beings.” Hoover’s view of people as individuals…

Major depressive disorder is a mood disorder characterized by the DSM-5 of depressed mood and markedly diminished interest or pleasure in nearly all activities occurring nearly every day, for most of the day, as indicated by a subjective self-report or an observational report from others. Also seen in individuals who have depression is significant weight loss, insomnia or hypersomnia, psychomotor agitation, fatigue and loss of energy, feelings of worthlessness or excessive guilt, diminished…

Neuronal regeneration is a high energy demanding process however, with maturation, axonal mitochondria transport progressively declines. Mitochondria are cellular powerhouses that supply ATP; essential for neuron growth, survival, and regeneration. Motile mitochondria can become stationary and in mature axons of the central nervous system (CNS), the majority of the mitochondria become stationary with only about 20-30% remaining motile. With this reduction in mitochondrial transport, mature CNS…

A career in cancer research has been my objective since before I entered college. My extensive personal experiences with this disease have deeply impacted my goals and aspirations as both a scientist and as a student. Unlike many undergraduates, I have accumulated an extensive amount of research experience during my undergraduate career, working to answer a broad range of biological questions. These diverse experiences have directly impacted my decision to pursue a graduate degree in immunology,…

The moment you step into the exhibition “A New Republic” by Kehinde Wiley on the fifth floor of the Brooklyn museum, you are embraced with a sense of equality. You look around and all you see are black men and women captured in various mediums by the artist where you can clearly see the uniqueness. At the center of the exhibit are glass stain portraits; sculptures surround half the room and the other half has 22k gold leaf, oil on wood panel or oil on linen paintings. The paintings are large in…

1. The innate immune system, also considered the first line of defense, is made up of different mechanisms that protect the host from infecting organisms. This system allows for immediate response to infection, and is found in all classes of plant and animal life. Though the innate immune system does provide immediate defense against an infecting agent, it does not provide long term protective immunity to the host, therefore it does not have memory. The innate immune system utilizes protective…

Starting in the mid-1800s a revolutionary movement began to root itself among the American population and other cultures around the world, Women’s Rights. In the push to raise awareness of the oppression of women and the inequality of sexes women traveled the country speaking to anyone that would listen. Two women stand apart in the effectiveness and remembrance of the speeches, as well as their leadership positions and impact they left on the nation in the development of equality. In the early…