Superoxide dismutase

Anthony Alvarado Bio 1A Chronic oxidative stress via hydroxyl radical and imbalanced redox homeostasis Redox hemostasis has been shown to be an important factor in the overall aging and neurodegeneration processes in mammalian models; such as, Alzheimer’s and Parkinson’s. As a result, redox homeostasis has been a key point of interest in current research. Redox homeostasis is the balance between electrophiles and nucleophiles in a system, more importantly in a biological system. These…

The effect of NS crude oil pretreatment on tumor volume Analysis of the data on tumor volume showed that a 4-month pretreatment with NS crude oil at the dose of 4 ml/kg/day results in significantly reduced volumes (550.46mm3±48.05; n=7) when compared to the control group (875.46.5mm3±80.17). NS1 tumor volumes (1322.83mm3±128.8; n=7) were significantly larger than the control volumes (Figure 1). There were no significant differences in mean volume of tumor tissue between NS2 and control group.…

Amyotrophic Lateral Sclerosis, more formally known as ALS or Lou Gehrig’s disease, is a neurodegenerative disease, causing the selective degeneration of both upper and lower motor neurons, as well as those in the motor cortex portion of the brain, which ultimately leads to the limited to complete loss of all voluntary muscle function. Now while the main pathology of ALS is the selective death of the previously mentioned motor neurons, more recent studies have suggested that the homeostatic…

Down Syndrome is the most prevalent and recognizable chromosomal abnormality in live born children, with a current prevalence of 2.8 out of 1000 children born with the genetic disorder [1]. In 1866, John Langdon Down termed the condition “mongolism” before it was later termed Down syndrome in honor of his discovery. Nearly a century later, geneticists Jerome Lejeune and Patricia Jacobs reported the chromosomal abnormality for the first time in humans to be secondary to a trisomy of chromosome 21…

beginning of the research and one month after the end of the trial. In order to measure the quantities of antioxidants, the Flandox Total Antioxidant Status kit was used. The use of this kit allowed for a correct measurement of the levels of superoxide dismutase, glutathione reductase, and glutathione peroxidase. These 3 major antioxidants are innate, enzymatic antioxidants that can be found in every human organism. In order to analyze the levels and effect of TMA-Zeolite, scientists used the…

It is with great pleasure that I recommend Becky Gauthia for admission into dental school. I have worked with Becky in my capacity as a Professor and Academic Advisor at Norfolk State University for six years. She is a remarkable and tenacious student that I strongly believe will be successful in your program. The first time I met Becky, she came to my office looking for assistance with registering for her current semester’s courses. To my surprise, she had taken the initiative prior to our…

limited to muscle tightness and weakness, slurred speech, cramps, difficulty eating, and an extreme weakness to a particular limb [Website]. The twenty-first chromosome is known to be linked to Amyotrophic Lateral Sclerosis as well as the mutated superoxide dismutase (SOD1) protein that is currently being studied close to determine if it has…

Abstract The aim of the present study was to investigate the effects of Cichorium intybus on lipid peroxidation activities of both enzymatic and non-enzymatic antioxidants, inflammatory mediators, myocardial enzymes and histopathology of cardiac tissues in experimental diabetic cardiomyopathy (DCM). Diabetic cardiomyopathy was induced by single intraperitoneal injection of STZ (40mg/kg) combined with high energy intake in rats. Seed extract of Cichorium intybus (CIE) (250mg/kg & 500mg/kg) was…

significantly increased treadmill running times. The end result is improved exercise endurance performance. Resveratrol itself has antioxidant properties and upregulates cellular mechanisms of oxidative resistance by inducing mitochondrial superoxide dismutase in human cells. The cardioprotective effects of resveratrol and other polyphenols may be in part to their ability to decrease LDL cholesterol oxidation, and therefore the pro-inflammatory cascade that ultimately leads to atherosclerotic…

Superoxide dismutase 1 (SOD1) is a gene that has been linked to familial ALS (FALS); it results in the formation of free radicals inside the cell that disrupt cellular functions. Astrocytes are one of the cells affected by free radicals; the free radicals disrupt…