Succinate dehydrogenase

Chemistry: Enasidenib is a first in class, a selective allosteric inhibitor of mutant isocitrate dehydrogenase-2 (IDH2) inhibitor discovered at Agios Pharmaceutical, Inc. in the United States of America. Recently, on 1 August 2017, Celgene Corporation and Agios Pharmaceutical in cooperation won the approval for Enasidenib under brand name IdhifaTm for the treatment of relapsed/refractory acute myeloid leukemia. it is a white to off-white crystalline, non hygroscopic powder existing in…

4.2.3.5. Antioxidant assays in gastric tissue homogenate 4.2.3.5.1. Catalase activity Catalase activity in the gastric tissue was measured according to the procedures of Sinha (1972). One ml of homogenate solution was taken and mixed with 5 ml of phosphate buffer of pH 7.4. To this 4 ml of 0.2 M H2O2 was added and time noted. Exactly after 180 seconds of adding H2O2, a set of 1ml of reaction mixture from the above was taken and 2 ml dichromate acetic acid was added. It was then kept in a boiling…

Brazilian Jiu-jitsu Brazilian Jiu-jitsu, or BJJ, is a style of martial arts, modified from the ancient Japanese art of Jiu-jitsu by the Gracie family and others, based on using an opponent’s momentum and leverage against them for defense. It involves take-downs and grappling, and has become a large sport that can be seen incorporated in the televised sport Mixed Martial Arts, or MMA. BJJ is a high intensity sport that involves endurance training as well as resistance training and explosive…

Introduction The scientific study of Huntington’s Disease (HD) had began in 1872, by George Huntington who is a family physician that had published a report on the clinical symptoms and peculiar mode of inheritance of the disorder.(1, 2) Huntington’s disease has 3 subtypes according to the age onset, which are infantile, juvenile and the adult-onset.(2) Individuals with Huntington’s disease can become asymptomatic between the ages of 1 and 80 years.(3) The typical mean age of onset is 40 years,…