Striatum

Obsessive compulsive disorder(OCD) is anxiety disorder that people have unwanted thoughts, ideas, or sensations(obsessions) that will make them want to something repetitively. Some common compulsive disorders are double checking things to see if they're good or checking in on loved ones to see if they are safe. A lot of people do these things but to be classified as having Obsessive Compulsive Disorder the patient compulsions need to be so extreme that it interferes with there important actives…

The patient (pt) in room 584 is an 84-year-old Caucasian woman who was transferred to Lynchburg General hospital on December 12, 2016 from Stonewall hospital in Lexington in order to receive pulmonary care. Though she was admitted for unspecified dementia without behavioral disturbances, she was originally hospitalized at Stonewall since September 21, 2016 for atrial fibrillation with a low ventricular response rate, and dyspnea. She has co-morbidities of Parkinson’s disease and Lewy body…

According to Gould, (2010). different studies have shown the negative effects of drug use on working memory: Morphine has been shown to impair working memory (Friswell et al.,2008); polydrug users who preferred cocaine or heroin, continued to have cognitive impairments, including working memory, up to five months into abstinence (VerdejoGarcía, and Pérez-García, 2007); methylenedioxymethamphetamine (MDMA, ecstasy) caused working memory impairment even two and a half years after cessation of use…

Adolescents and Inexperience cause an Untimely Death Romeo and Juliet are children when they fall in love, and too young when they decide to take their own life. The story of Romeo and Juliet and their “untimely death” is caused by their inexperience, their eagerness, their curiosity and mainly their youth. Every action they undergo they are just too young to for. It is understandable though, they are teenagers and teenagers are very spontaneous, but their age is not the only thing to blame.…

arc Lewis, a developed neuroscientist, was once an addict himself. At certain points in his life he had addictions to cough medicine, alcohol, marijuana, methamphetamine, LSD, heroin, nitrous oxide, and forms of opium, so with good reason, the topic of addiction, its definition, and its causes are very personal and dear to his heart. Lewis’s biggest point he wanted to share during his talk was that addiction is not a disease, not a person with wrongful morals, and not a dichotomy. In the rest of…

Source 1: Abusing marijuana blunts the brain's ability to respond to dopamine, the neurotransmitter that's responsible for our feelings of pleasure, motivation, and reward. Many abused substances stimulate brain dopamine signaling - the mechanism underlying the rewarding effects of drugs, food, and sex. Both groups produced just as much extra dopamine after taking the drug, but the marijuana abusers had significantly blunted behavioral, cardiovascular, and brain dopamine responses to the…

Synaptic dysfunction: Studies in a number of the PARK2 knockout lines suggest the presynaptic dopamine transmission is perturbed. In the Park2tm1Shn knockout line, the evoked dopamine signal of neurons was reduced and could not be restored with DAT inhibition (Goldberg et al., 2003). The normal function of Parkin in dopaminergic synaptic transmission is been explored and found that the signal is lower in parkin-/- mice relative to the control, indicating that loss of Parkin indeed decreased DA…

serine-threonin kinase that when activated, promotes protein translation and cell growth in the brain. mHTT causes a genetic defect of deleting a key component that activates the mTORC1 called Ras homolog enrich in the brain (Rheb) and also in the striatum (Rhes). Rhes itself plays an important role against the transfected mHTT cells by providing neuroprotection. (Lee et al., 2015) When mTORC1 becomes inactivated or when Rhes becomes reduced, many interactions becomes disrupted or changed.…

social media. Upon my observation it seems like this study was primarily guided through past research. For example, the experimental cover story was guided by past research on how the processing of positive social feedback was processed in the ventral striatum. I found the format of this article challenging to understand. The article was translated from German and we have different guidelines to writing an article. However, I wish there was a section specifically discussing research aims. I…

dopamine in the brain. Antipsychotics block certain amounts of dopamine, depending on potency. These medications block the dopamine receptors in the brain, causing a cutoff of the neurotransmitter. While this helps in areas such as the thalamus and striatum to regulate emotional and motivated behavior and facilitate organized thought in schizophrenics, it also blocks areas such as the cerebellum which involves the fine tuning of motor movement causing undesirable side effects (Mueser and…