Striatum

This section introduces the background of gene therapy in Parkinson’s Disease, especially on brain cells targeting therapy. It provides the rationale for further proposal of brain cell targeted PD therapy based on Ultrasound-meditated microbubble delivered AAV vector or RNAi. 1.Parkinson’s Disease, a common CNS disorder with no adequate treatment in pharmacological approaches Parkinson's disease (PD) is a progressive, central nervous system (CNS) disorder, belonging to a group of conditions…

Love is an intense feeling endured by many individuals, for it unleashes a great deal of hormones and chemicals that cannot be resisted. At its zenith, love seems to control the mind like a drug. When we fall head over heels for someone, our brain signals feelings of pleasure, closeness, and comfort. According to an online article, it states that that complex organ inside our head is hardwired to want love and keep love at all costs—a response that has been crucial to the survival of our…

The Parkinson is a disease that make Causes damage to the brain For lack of a neurotransmitter that is called dopamine and they are asked to be dopamine, dopamine is a neurotransmitter for the brain to send impulses to the motor nerves of the human body so that the body's bodies can work better and is important in all nerve responses that are related to the expression of emotions; Can be administered dopamine in the treatment of various types of shock like the Such as Parkinson's tremor Which…

from one object to another. The FEF produces saccade movement through four major pathways, “(1) a projection to the ipsilateral superior colliculus concentrated in the intermediate layers, (2) a pathway through the basal ganglia via the ipsilateral striatum, (3) a projection to the cerebellum via the pontine nuclei, and (4) a weaker projection to mesencephalic and pontine nuclei that make up the saccade generator circuit” (Schall…

are doing if you keep going back and forth between multiple of tasks. According Schultz “ when you put your attention from task to task, though, the information can’t be processed quickly enough, It’s sent to another part of the brain called the striatum, which is responsible for planning movements and motivation rather than storing data”. Then, if it keeps gathering information it's sent to the an area of your brain called the posterior lateral frontal cortex .When it's sent there than it is…

Aging in the brain is a complex process that involves several systems and structures. As the brain ages, there is a decreased activity in neurotransmission and increased risk for the development of neurodegenerative diseases. Dysfunction of the central noradrenergic and dopaminergic systems is one of the biological characteristics of aging in the brain and may contribute to changes in cognitive and motor functions in old individuals. Furthermore, aging-dependent norepinephrine (NE) loss occurs…

Introduction The Eating Disorders (ED) of Anorexia Nervosa (AN) and Bulimia Nervosa (BN) are two psychiatric disorders characterised similarly by abnormal feeding behaviours whose aetiology currently remains undiscovered. As outlined by the DSM-IV (1994), AN is distinguished as the refusal by an individual to maintain body weight at or above the normal minimum weight for their age and height. Further characteristics include an extreme fear of becoming overweight and a disturbance in the way the…

from imaging studies” by N.D. Volkow, J.S. Fowler, and G. Wang from The Journal of Clinical Investigation A cursory scan of the articles reveals a common understanding of how dopamine (DA) neuron levels affects the amygdala, hippocampus and dorsal striatum, all front cortical structures related to types of memory. Long-term use floods these areas, whereas withdrawal leads to dysfunction, which affects the functionality of these structures. These articles bespeak of an imbalance between reward…

in the periaqueductal gray, the right ventromedial prefrontal cortex and the right lateral orbitofrontal cortex, which plays a significant role in processing emotion and empathy. The high psychopathy group experienced more activity in the dorsal striatum, the dorsomedial prefrontal cortex, and the posterior superior temporal sulcus…

second scan was then performed on the test group with induced anxiety. The study revealed that within the group with no obvious OCD symptoms, once anxiety is induced the striatum (subcortical part of the forebrain and a critical component of the reward system, Wikipedia) is activated. Within the group with OCD symptoms the striatum was not activated which is consistent with striatal…