Statin

Primary Angioplasty – A Life-saving Procedure Primary angioplasty is a term used to describe an angioplasty done as a life-saving emergency procedure in a patient with an on-going heart attack [PAMI - Primary Angioplasty in acute Myocardial Infarction]. The international accepted door to balloon time intervention is within 90 minutes and 3 to 6 hours from the onset of heart attack for PAMI. Doing angioplasty in a critical patient of heart attack is in itself challenging and doing so in the…

Coronary heart disease is a condition where the heart’s blood supply is reduced or completely blocked by plaque which is formed due to thebuildup of fats or other deposits in blood vessels of the blood circulatory system. Substances such as tar from cigarettes can also coagulate in the arteries and cause heart failure. A person suffering from coronary heart disease will find the earliest indication in a form of acute chest pain and this is usually referred to as angina (Coronary artery disease…

States the leading cause of death is heart disease among adults (Byrne et. al. 800). This has been partially attributed to high cholesterol levels in adults; the leading prescription drug in therapeutic category taken in adults over the age of 40 is statins used to lower cholesterol (Cardon and Showalter 5436). This is only one example of the drugs being prescribed in the United States that have no improved our overall health standing. If the drugs taken in America are not doing the job…

666). The statin drugs work by inhibiting an enzyme called HMG CoA reductase, when this enzyme is inhibited cholesterol biosynthesis is inhibited in the liver (Kee, et al., 2015, p. 666). This group of drugs has been helpful in decreasing coronary artery disease (CAD)…

When testing your cholesterol a blood test is tooken to check your cholesterol levels. It is usually called a lipid panel or lipid profile. For accurate results you are told to abstain from eating or drinking ( except water) for 9-12 hours before the blood sample is taken, to prevent misdiagnosis. Mechanism of Vytorin Stain Vytorin will decrease your LDL "bad cholesterol" and triglycerides. However it will increase your HDL "good cholesterol" Vytorin helps block the absorption of cholesterol…

Clinical Decision Making Pathophysiology: Cerebrovascular Accident (CVA) A cerebral vascular accident (CVA) is defined as “a sudden loss of brain functioning from a disruption of blood supply to a part of the brain causing temporary or permanent loss of movement, thought, memory, speech, or sensation”(Belleza, 2016, p. 1). CVA is categorized as ischemic or hemorrhagic. Hypertension accounts for the majority of ischemic CVAs or strokes. According to the American Heart Association, ischemic…

Coronary artery disease (CAD) results when our body’s coronary arteries become damaged. Our coronary arteries are important because “they supply our heart with blood, oxygen, and nutrients” (Coronary artery disease, 2014). Our arteries typically get damaged because of plaque and inflammation developing inside them. “The buildup of plaque causes our arteries to become narrower and that decreases our blood flow to our heart” (Coronary artery disease, 2014). This decreased blood flow can cause…

INTRODUCTION Lovastatin is a statin drug that decreases the total cholesterol level in patients diagnosed with hypercholesterolemia. The drug aims to prevent serious cardiovascular diseases such as heart attack due to blockage of arteries. Lovastatin acts as a competitive inhibitor for the HMG-CoA reductase enzyme in catalyzing the conversion of HMG-CoA to mevalonate, (Alberts, 1998). The drug is also hydrolyzes in vivo to active form β-hydroxyl acid, (Katz, 2005) and was recently researched on…

In Year 5 we had to dress up for a day as the person we wanted to be as an adult. I woke early and dressed in a white garment, instruments and tools tucked into my breast pocket, pad gripped in hand. I wanted to be an artist then but now I have made the decision to be a doctor. Being an imaginative youth, the human body: the intricate structures of electrical and biochemical pathways working, or not, in synchronisation, is something I found amazing but also terrible. Intellectually I was…

1. a) Heroin is an illegal drug which is highly addictive. b) Steroid is a drug used by athletes to make them perform better. c) Statin is a medical drug which is used to reduce cholesterol levels. 2. a) What is the purpose of the Phase 1 trial? The drug should pass laboratory first. This is to check if they are toxic and if they could treat disease. After that they will be tested on cells and whole organs to see how they react on chemicals. After that a drug will be tested on animals, to find…