Spectroscopy

The carbohydrates present on the cells surface can act as a receptor for many pathogens to facilitate cell-cell adhesion through which humans can be infected, for example, mannose binds pathogenic bacteria E. coli and sialic acid binds influenza virus. Therefore, cell surface can be mimicked by preparing SAMs of carbohydrates to study and understand different types of binding and inhibition studies in vitro. SAMs of carbohydrates are also used for detecting disease biomarkers and carrying drugs.…

procedures, including large amounts of chlorinated solvents. Current efforts are directed toward fabrication of a fast, reliable and inexpensive toxin detection device. I am currently analyzing chlorinated toxins in coastal samples using portable Raman Spectroscopy method. Since Korea is a peninsula they also are surrounded by water which is being contaminated by these toxins because it comes from polluted runoff from industries to households. While doing that I also can be a representative for…

acid concentrations on a regular basis (at the start of MLF and every seven days thereafter) until its completion (taken as the point when the malic acid concentration is equal to or lower than 0.3 gIL). This was done by Fourier-transform Infrared Spectroscopy (FT-IR) (WineScan FT120, FOSS Analytical, Denmark) as well as determination of the malic acid concentration with an enzymatic assay (Roche, Boehringer Mannheim,…

Phase Solubility results The phase-solubility diagram (figure 1) obtained was classified as AL type(20) because the apparent solubility of ISH increased linearly with β-CD concentration over the entire concentration range studies, thereby suggesting the formation of a water soluble complex. A slope value of less than one indicated that an inclusion complex in a molar stoichiometric ratio of 1:1 was formed between the drug and β-CD in solution. The stability constant (718.58 M–1), computed from…

Here in the United States there is a sport that virtually owns a day of the week. For many people, this sport, football is a way of life in a figurative sense. For very few, the most elite to put on the pads this game is literally their way of life. For playing this game, the reward is living the dream that all of them collectively dreamt from the time they first put on the pads in Pop Warner. Living this dream also comes with the perks of fortune and fame. Looked up to and loved as almost god…

The objective of work was to optimize, formulate, evaluate and compare the transdermal gel containing vesicle based: Transfersomes and liposomes, containing Ketoconazole, an anti-fungal bioactive. Ketoconazole loaded Transfersomes were prepared using thin film hydration method with different concentration of surfactant (Span80, Tween80, and Sodium Deoxycholate) and soya lecithin and characterized for various parameters including Vesicles Size, Morphology, Entrapment Efficiency, Drug Loading…

Figure 3. Possible reaction mechanism for the decomposition of ammonium perchlorate. Based on the findings from all of the used techniques, the species formed in the beginning are ammonium ion, oxygen and chlorine species. The decomposition products of ammonium ion were hydroxylamine, ammonia and nitrogen dioxide. The perchlorate ion loses one of the oxygen atoms and forms chlorate ion. The ammonia is lost in reaction through formation of hydroxylamine, which is formed in reaction between…

Forensics is defined as scientific tests or techniques used in connection with the detection of crime. The chemical advancements developed in this field stem from hundreds of years ago, where poisons, especially arsenic, were an extremely popular way of killing people. This led to the first organized criminal investigation using a chemical test in 1752. This was the Blandy Trail, where the suspected poison was arsenic, and tests were conducted to prove so. Some of these early tests include…

Objective The purpose of the experiment is to synthesize a compound with an organometallic iron-carbon bond and use infrared spectroscopy to investigate the unconventional sandwich structure. In addition, the experiment aims to understand pi-bonding of an arene ring, use cyclic voltammetry to understand the redox capacity of ferrocene, and explore the barriers between formal inorganic and organic chemistry definitions. Introduction Ferrocene was discovered unintentionally in 1949 when Miller…

Ultrafast Electron Microscopy has been demonstrated to be an effective table-top technique for imaging the temporally-evolving dynamics of matter with subparticle spatial resolution on the time scale of atomic motion. A stringent enhancement of the UEM temporal resolution is demanded for recording snapshots of the electron motion which will provide a real-time access to all microscopic motions outside the atomic core and radically change our insight into the workings of the microcosm. Here, we…