Soy protein

Insulin Receptor Introduction Insulin receptor (IR) is a transmembrane receptor, an important member to a large family of tyrosine kinase receptor proteins. Endogenous ligands such as insulin, IGF-1 (Insulin-like growth factor-1) and IGF-2 (Insulin-like growth factor-2) bind to this receptor to carry out major physiological and metabolic functions. INSR (Insulin Receptor) gene encodes a preproprotein that is proteolytically processed in our body to form a functional heterotetrameric insulin…

The Shakeology shake is hands down the most nutritious and all rounded shake in the market today. At only $4, one serving of this delicious shake is equivalent in nutrition value to the following; Romaine lettuce- 3 cups Raw broccoli- 4 cups Exotic fruit- 1 bowl Raw cauliflower- 10 cups Raw mushrooms- 4 cups Wheat grass- 1 shot Raw onions- 3 pieces Raw carrots- 7 pieces Peas- 1 cup Red radishes- 4 cups Nonfat yoghurt- 4 cups Market research shows that purchasing all these ingredients separately…

GBA1 MUTATIONS INTERFERE WITH WNT/β-CATENIN SIGNALING AND LINEAGE DIFFERENTIATION IN GAUCHER IPSC-DERIVED NEURONAL PROGENITORS. Robert Liu*, Ola Awad, and Ricardo Feldman, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD. Gaucher disease (GD) is an inherited lipid-storage disease caused by mutations in the acid beta-glucocerebrosidase gene (GBA1). Mutant glucocerebrosidase (GCase) leads to the accumulation of glucosylceramide and neurotoxic…

A 12-well tissue culture plate was used to carry out the LIVE/DEAD Assay. Well “A” contained the untreated HepG2 cells. Well “B” contained camptothecin, which is used as a control for killing the HepG2 cells instead of the use of plumbagin. Well “C” contained the compound Epigallocatechin Gallate. Well “D” remained empty, because a vehicle treatment is not needed for this experiment. Each well contained 1 ml of HepG2 cells. A negative and positive control where both set up in the 12-well tissue…

As briefly mentioned before, atropine acts as an antagonist on acetylcholine because its chemical structure is similar to acetylcholine. Thus, structure is an important feature of the atropine molecule that is imperative to understanding its effects on the body. Although today’s chemists know the chemical structure of atropine, the conformational flexibility of the molecule is still poorly understood. A conformation is any three-dimensional arrangement of atoms within a molecule that results…

the ability to become regulated by responding to cellular or environmental signals. This is done by controlling the water transport occurring at an individual protein level through conformational changes, such as gating. The following one involves regulating at the transcriptional/translational level in addition to trafficking, in which protein molecules are rotated throughout intracellular storage vesicles, as well as target membranes. Aquaporins allow for quick and specific regulation, in…

University researchers studying the biology of aging demonstrated a new strategy for stimulating autophagy - the process by which cells rebuild themselves by recycling their own worn-out parts. The process of autophagy involves rounding up misfolded proteins and obsolete organelles within a cell into vesicles called autophagosomes. The autophagosomes then fuse with a lysosome, which breaks down the cellular macromolecules and converts them into components the cell can re-use. Louis Lapierre, an…

Hairstyles of any length can easily be maintained with clip in extensions. All hair types, from thick to medium, to thin can utilize hair extensions. Brown Blonde micro loop extensions are easy to use, and can add natural flare to any style. To make hair blend more naturally, micro loop extensions will do just that. The reason they are capable of creating such a natural look to a persons hair is because of their unique design. They are individual pieces of hair that are bundled together that…

Adiponectin is a cytokine exclusively produced and secreted by adipocytes. In mice, adiponectin decreases hepatic lipogenesis and increases FFA oxidation. In humans, several studies have shown an inverse correlation between adiponectin levels in the blood and hepatic insulin sensitivity as well as fat content in the liver. Adiponectin is a cytokine which acts as an anti-steatotic factor in both muscle and hepatocytes, probably by activating Peroxisome proliferator-activated receptor gamma…

Hypermetabolism is the physiological condition of increased rate of metabolic activity and is described by a strange increment in the body's basal metabolic rate. Hypermetabolism is caused by injury or multiple traumas to the body. This could be in the form of surgery, bone fractures, infections, burns and bone marrow transplant. Hypermetabolism is a symptom of hyperthyroidism which is characterised by an increment in the production of thyroid hormones hence an increase in the rate of cellular…