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    Genetic Disruptions

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    alterations can cause a range of phenotypic effects from no effect to cell death for essential genes. Disruptions that result in an essential phenotype are typically important to core activities of the cell, such as energy metabolism, DNA replication, or protein processing. Mutations can also have complex buffering effects, where a mutation that would normally have a phenotypic effect but does not while in the…

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    Rac-Raw Research Paper

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    Downstream Targets Due to the lack of developing an effective Ras treatment, some have turned to targeting downstream effectors of Ras. Downstream effectors have a critical role in Ras carcinogenesis and are commonly found in KRAS mutated cancers. The most intensely targeted pathways are the Raf-MEK-ERK (MAPK) and PI3K-AKT-mTOR signaling pathways. Raf-MEK-ERK MAPK signaling is initiated through receptor tyrosine kinases after their activation by growth factors (Mccubrey 2006). Once Ras is in its…

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    discover what kinds of amino acids your body needs and when to take them. It’s amazing that so many bodybuilders know so little about amino acids considering how vital they are to overall health and muscle growth. Muscle building amino acids are what proteins are made out of; therefore they ultimately become part of your muscles and the rest of your body. They affect many different functions in the body including how much energy we have, our mood as well as muscle development and recovery.…

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    Gba Research Paper

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    are protein molecules that receive chemical signals in the form of ligands and induce responses at cellular level. They are localized at the cell surface, cytoplasm or the nucleus, depending on their amino acid sequences. In addition to using these three different localizations to categorize receptors, the types of action of receptors are also used as a mean of classification. The four main classifications of receptors are: 1. Ionotropic (or ligand-gated ion channel) receptors, 2. G-protein…

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    A. What is the purpose of a polymerase chain reaction (PCR)? List the four main components of a PCR. (2 points) The purpose of a PCR is to make large amounts of DNA segments from just a specific DNA sequence. This method is used to scientifically prove if a suspect of committing a crime is truly the person who committed the crime. The four main components of a PCR are: DNA from a sample, nucleotides A, T, G, C, DNA polymerase, and primers. B. What is gene expression? List the two steps of…

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    in kilobases) (1.2+0.7+0.4+3.1) = 5.4 kb. d) RNA Protein Truncation mutation in exon 2 Same length, same amount of RNA produced. Shorter in length (due to earlier stop codon), same amount of protein produced, usually changes the protein to non-functional, though not always. 3bp in frame deletion in exon 1 Shorter in length by 3pb, same amount of RNA produced. Shorter in length, same amount of protein produced, usually causes the protein to become non-functional, though not always. Splice…

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    cell growth, cellular differentiation, cell adhesion, the movement of cells and the death of cells. The body is unable to produce ceramidase with Farber’s disease, thus causing the buildup of ceramide. A gene is a section of DNA that codes for one protein. When there is a mistake in the…

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    Enzyme Peroxidase Essay

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    cells as a byproduct of photorespiration, photosynthesis or cellular respiration. This is significant because an enzyme operating in nonoptimal pH could have negative effects on the cell, and could pose a health threat to the organism. Enzymes proteins that speed up chemical reactions by lowering the activation energy. They do this by acting as a template for substrate orientation, stressing the substrates and stabilizing the transition state, providing a favorable microenvironment, or…

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    separated from the cytoplasm by the outer and inner mitochondrial membrane.The outer membrane is porous and freely traversed by ions and small, uncharged molecules through pore-forming membrane proteins (porins), such as the voltage-dependent anion channel VDAC [19]. Any larger molecules, especially proteins, have to be imported by special translocases. Because of its porosity, there is no membrane potential across the outer membrane. By contrast, the inner membrane is a tight diffusion barrier…

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    Yeast Enzyme Lab Report

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    Introduction: All organisms depend on the action of enzymes to carry out the reactions of life. According to the text in Campbell Biology, enzymes are biological catalysts. These globular proteins speed the rate at which metabolic processes occur by lowering the activation energy or the energy barrier required to transform reactants to products. Each enzyme is specific, each containing active sites destined for a substrate. Substrates are the reactants or starting materials of chemical…

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