Sonic hedgehog

We all spent 9 months in our mother’s womb. For some of us, the whole process goes according to plan but for others, one small change can cause dramatic results. When someone has a genetic condition, that means that something went wrong while they were developing in the womb. I can name three genetic conditions that result from a problem in early development. This first condition occurs at 2 weeks and 5 days. It’s called big baby syndrome and it happens when two copies of the fathers growth…

also shares a high degree of homology with the GLI family; elegans sex determination gene, and the Xenopus transcriptional factor TFIIIA. GLI proteins are found in humans and possess the same characteristics of mutations of the Ci protein. The Sonic Hedgehog (Shh) signaling play a vital role in limb development and call death in the nervous system during development. Although it is not quite clear what the purpose of PKA is but it does play an essential role in Drosophila embryonic development…

occurred when the tissue was removed later, and undergrowth occurred when removed early. This was an extremely important finding because they found out that this was occurring because one single gene, and this was the discovery of the Sonic Hedgehog Gene. The Sonic Hedgehog Gene, was initially found in fruit flies as something that told other cells what to do, making different parts. However, later, the gene was found in chick embryos that linked the gene in the ZPA tissue to the creation of…

Why do we look the way we do? What does the human hand have in common with the wing of a fly? Are breasts, sweat glands, and scales connected in some way? To better understand the inner workings of our bodies and to trace the origins of many of today's most common diseases; we have to turn to unexpected sources: worms, flies, and even fish. In Your Inner Fish, Neil Shubin clears up the questions previously asked. He tells the story of evolution by tracing the organs of the human body back…

in which there is an incomplete cleavage of prosencephalon into the left and right hemispheres which occurs sometime between the 18th and 28th day of gestation. The primary defect is the lack of forebrain tissue which is impacted by a lack of sonic hedgehog signaling which causes the facial defects. During the 4th week of gestation, the neural tube gives rise to the three primary brain vesicles prosencephalon, mesencephalon, and rhombencephalon. In the 5th week of gestation, the prosencephalon…

Your Inner Fish by Neil Shubin Chapter Questions Chapter 1 – Finding Your Inner Fish 1. Explain why the author and his colleagues chose to focus on 375 million year old rocks in their search for fossils. Be sure to include the types of rocks and their location during their paleontology work in 2004. The author and his colleagues chose to focus on 375 Million Years as it was a period when the transformation took place from fish to fish with limb. The fish without characteristics of…

How much do you know about what influences our culture? Did you know Japan is one of the biggest influences on our culture? Everything from furniture, entertainment, and even our own homes are influenced by Japanese culture. We wouldn’t have most of the things we have today if it wasn’t for Japan. We often forget to stop and think about all the things we wouldn’t have if it wasn’t for other countries bringing their culture into America. Japanese culture first came to America when Japan agreed…

The developments of cancer in children have had many disagreements between scientist and researchers. Some might agree that it hard to determine what causes cancer in children. Scientist around the world has developed their own theories on the development of cancer in children. Although there are disagreements, many of the scientists have come to the conclusion that some forms of cancer have been the linked to genetic cells that are formed through fertilization of the embryo, which could be…

In Neil Shubins’ “Your Inner Fish: A Journey Into the 3.5-Billion-Year History of the Human Body”, he takes the audience on the journey of the discovery and history of how different organisms and adaptations have converged to form a relationship between fish and tetrapods. Shubins first relates the evolutionary fact that humans and other forms of “tetrapods’ major body systems have developed from fish and sharks” (20), through his time on the field as a paleontologist. He describes his multiple…

have all held witness to history and all its extraordinary events. We all have seen the time cycle when the past shall become the present and present shall become the past. We have seen history repeats since the beginning of time, but just like Sonic the hedgehog, it all goes so fast. Sometimes as people we don't quite catch grasp of what’s occurring while in reality and things just slip away. Take the western frontier and the Chicago’s destruction of the projects for an example. The Western…